CAJ | 학술논문

目的探讨小剂量硝酸甘油在心肺复苏术中的临床疗效.方法将我院重症监护病房中发生心脏骤停的患者按随机数字表法分为对照组(127例)和试验组(132例),对照组按照《2010年国际心肺复苏和心血管急救指南》进行急救,胸外心脏按压,液体扩容,肾上腺素静脉注射,多巴胺、多巴酚丁胺升压,呼吸机辅助呼吸等综合治疗,试验组在对照组治疗的基础上,加用小剂量硝酸甘油(5 μg/min)微量泵泵入,比较两组患者心脏复苏成功率,复苏成功时间,有创动脉血压及24h存活率.结果试验组患者心脏复苏成功率及24h存活率、复苏成功时间与对照组比较差异有统计学意义(P＜0.05)；两组患者有创动脉血压比较差异无统计学意义(P＞0.05).结论心肺复苏术中应用小剂量硝酸甘油可明显提高心肺复苏成功率,提高患者存活率,并且对外周动脉血压无明显影响.
목적 탐토소제량초산감유재심폐복소술중적림상료효.방법 장아원중증감호병방중발생심장취정적환자안수궤수자표법분위대조조(127례)화시험조(132례),대조조안조《2010년국제심폐복소화심혈관급구지남》진행급구,흉외심장안압,액체확용,신상선소정맥주사,다파알、다파분정알승압,호흡궤보조호흡등종합치료,시험조재대조조치료적기출상,가용소제량초산감유(5 μg/min)미량빙빙입,비교량조환자심장복소성공솔,복소성공시간,유창동맥혈압급24h존활솔.결과 시험조환자심장복소성공솔급24h존활솔、복소성공시간여대조조비교차이유통계학의의(P＜0.05)；량조환자유창동맥혈압비교차이무통계학의의(P＞0.05).결론 심폐복소술중응용소제량초산감유가명현제고심폐복소성공솔,제고환자존활솔,병차대외주동맥혈압무명현영향.
Objective To explore the clinical efficacy of less dose nitroglycerin during CPR.Methods ICU in cardiac arrest patients were randomly divided into two groups,control group according to the 《2010 international guidelines for cardiopulmonary resuscitation and emergency cardiovascular care》first aid,chest compressions,liquid expansion,intravenous administration of epinephrine,dopamine,dobutamine boost,assisted mechanical ventilator therapy,experimental group in the control groups based on treatment,combined with little dose nitroglycerin ( 5 μg/min ) with micro pump,compared two groups of patients with cardiac resuscitation success rate,recovery time,arterial blood pressure,24 hour survival rate.Results in the trial group,cardiac resuscitation success rate and 24 hour survival rate,recovery time is shortened,the difference has statistical significance ( P ＜0.05 ); two groups of invasive arterial blood pressure difference was not statistically significant ( P ＞ 0.05 ).Conclusion CPR in the application of less dose of nitrog-lycerin can significantly improve the success rate of cardiopulmonary resuscitation,prolong the survival,and the peripheral artery blood pressure had no significant effect.