CAJ | 학술논문

目的：观察外用中药珠黄霜对肛门术后创面肉芽组织中羟脯氨酸(Hyp)含量的影响。方法：将50例低位单纯性肛瘘术后患者随机分为珠黄霜治疗组和马应龙麝香痔疮膏阳性药物对照组，分别在术后第3、7、14天创面肉芽组织上取材，应用碱水解比色法检测Hyp的含量。结果：术后第7、14天创面Hyp含量治疗组显著高于对照组，第3天两者差异无显著性。结论：珠黄霜能显著提高肛门术后创面肉芽组织中Hyp的含量。
목적：관찰외용중약주황상대항문술후창면육아조직중간포안산(Hyp)함량적영향。방법：장50례저위단순성항루술후환자수궤분위주황상치료조화마응룡사향치창고양성약물대조조，분별재술후제3、7、14천창면육아조직상취재，응용감수해비색법검측Hyp적함량。결과：술후제7、14천창면Hyp함량치료조현저고우대조조，제3천량자차이무현저성。결론：주황상능현저제고항문술후창면육아조직중Hyp적함량。
To observe the effect of Zhuhuang Frost (ZHF), an external preparation of Chinese herbal medicine, on level of hydroxy-proline (Hyp) in surgical wound after anal operation. Methods: Fifty postoperational patients after low position simple operation of anal fistula were randomly divided into two groups and treated with ZHF and Mayinglong Musk hemorrhoidal paste (MMHP) respectively. The level of Hyp in granulation of wound was tested using alkaline hydrolysis assay at the 3rd, 7th and 14th day after operation respectively. Results: The Hyp level tested at the 7th and 14th day after operation in the ZHF treated group was higher than that in the MMHP treated group, but those tested at the 3rd postoperational day in the two groups was not different significantly. Conclusion: ZHF could increase the Hyp level in postoperational granulation of wound after anal operation.