CAJ | 학술논문

从中药山柰的混杂品种苦山柰根茎分得一个新二萜苦山柰萜醇(marginatol 1)和5个已知化合物:8(14),15-sanderacopimaradiene-1α,9α-diol(2),8(14),15-sanderacopimaradiene-1α,6β,9α-triol(3)以及吉马酮(4),对-甲氧基-肉桂酸乙酯(5)和正-十五烷(6).根据光谱数据(IR,MS,1H-1H,13C-1H NMR,NOESY和HMBC)分析,确定苦山柰萜醇(1)的化学结构为8(14),15-isopimaradiene-6α-ol.化合物2,3和4是首次从该植物分得.
종중약산내적혼잡품충고산내근경분득일개신이첩고산내첩순(marginatol 1)화5개이지화합물:8(14),15-sanderacopimaradiene-1α,9α-diol(2),8(14),15-sanderacopimaradiene-1α,6β,9α-triol(3)이급길마동(4),대-갑양기-육계산을지(5)화정-십오완(6).근거광보수거(IR,MS,1H-1H,13C-1H NMR,NOESY화HMBC)분석,학정고산내첩순(1)적화학결구위8(14),15-isopimaradiene-6α-ol.화합물2,3화4시수차종해식물분득.
Marginatol (1), a new isopimarene diterpenoid, and five known compounds 8(14),15-sandera-copimaradiene-1α,9α-diol (2), 8(14),15-sanderacopimaradene-1α,6β,9α-triol (3), germacrone (4), trans-ethyl p-methoxycinnamate (5) and n-pentadecane (6) were isolated from the hexane extract of Kaempferia marginata Carey.The structure of marginatol (1) was established as 8(14),15-isopimaradiene-6β-ol on the basis of spectral data (IR,MS, 1H-1H, 13C-1H NMR, NOESY and HMBC). Compounds 2, 3 and 4 were isolated for the first time from this plant.