医药导报
醫藥導報
의약도보
HERALD OF MEDICINE
2001年
3期
180-181
,共2页
邱栋发%黄窕姮%张招莲
邱棟髮%黃窕姮%張招蓮
구동발%황조항%장초련
昂丹司琼%甲氧氯普胺%肺癌%化学治疗%呕吐
昂丹司瓊%甲氧氯普胺%肺癌%化學治療%嘔吐
앙단사경%갑양록보알%폐암%화학치료%구토
目的：评价单剂昂丹司琼对肺癌化疗所致恶心、呕吐的预防作用。方法：选择35例肺癌化疗患者，采用自身交替对照的方法，观察单次静脉注射昂丹司琼8 mg对化疗所致恶心、呕吐的预防作用。结果：单剂昂丹司琼对肺癌化疗所致恶心、呕吐的控制率分别为91.4%，94.3%；甲氧氯普胺的控制率分别为65.7%，74.3%，两者比较差异显著。结论：单剂昂丹司琼对肺癌化疗所致恶心、呕吐有明显的预防作用。
目的：評價單劑昂丹司瓊對肺癌化療所緻噁心、嘔吐的預防作用。方法：選擇35例肺癌化療患者，採用自身交替對照的方法，觀察單次靜脈註射昂丹司瓊8 mg對化療所緻噁心、嘔吐的預防作用。結果：單劑昂丹司瓊對肺癌化療所緻噁心、嘔吐的控製率分彆為91.4%，94.3%；甲氧氯普胺的控製率分彆為65.7%，74.3%，兩者比較差異顯著。結論：單劑昂丹司瓊對肺癌化療所緻噁心、嘔吐有明顯的預防作用。
목적：평개단제앙단사경대폐암화료소치악심、구토적예방작용。방법：선택35례폐암화료환자，채용자신교체대조적방법，관찰단차정맥주사앙단사경8 mg대화료소치악심、구토적예방작용。결과：단제앙단사경대폐암화료소치악심、구토적공제솔분별위91.4%，94.3%；갑양록보알적공제솔분별위65.7%，74.3%，량자비교차이현저。결론：단제앙단사경대폐암화료소치악심、구토유명현적예방작용。
Objective:To evaluate the effect of single-dose ondansetron in prevention of chemotherapy-induced nausea and vomitus in lung cancer patients.Methods:35 lung cancer patients receiving chemotherapy were observed with self-comparisonal design.A single dose of 8mg ondansetron and of 20mg metoclopramide were administered by intravenous injection and intramuscular in jection to the patients at different time and the outcome was observed.Results:The control rates of nausea and vomitus by ondansetron were 91.4% and 94.3%,and 65.7% and 74.3% by metoclopramide respectively(P＜0.05).Conclusion:A single-dose of ondansetron can effectively prevent nausea and vomitus in lung cancer patients caused by chemotherapy.
