西北国防医学杂志
西北國防醫學雜誌
서북국방의학잡지
MEDICAL JOURNAL OF NATIONAL DEFENDING FORCES IN NORTHWEST CHINA
2001年
2期
103-105
,共3页
杨生岳%冯恩志%郭玉枝%索玉梅%张瑛%高玲%董红梅%赵丽红
楊生嶽%馮恩誌%郭玉枝%索玉梅%張瑛%高玲%董紅梅%趙麗紅
양생악%풍은지%곽옥지%색옥매%장영%고령%동홍매%조려홍
高原%慢性阻塞性肺疾病%气流阻塞
高原%慢性阻塞性肺疾病%氣流阻塞
고원%만성조새성폐질병%기류조새
目的：比较FEV1占预计值百分比(FEV1％)与FEV1／FVC比值(FEV1／FVC)对判断高原COPD气流阻塞的应用价值。方法：对比分析了海拔2 260～3 900 m地区86例COPD、32例限制性通气功能障碍患者和30例健康人的FEV1％与FEV1／FVC。结果：COPD组FEV1％与FEV1／FVC呈正相关(r＝0.897，P＜0.01)。依FEV1％＜82％、FEV1／FVC＜77％作为判断气流阻塞标准，COPD组分别为87.21％和86.05％，限制组分别为84.38％和12.50％(P＜0.01)。作为COPD分级标准，FEV1％与FEV1／FVC的下降不一致，Ⅱ、Ⅲ级FEV1／FVC显著高于FEV1％(P＜0.01或P＜0.05)，Ⅰ级略低于FEV1％(P＞0.05)。结论：FEV1％和FEV1／FVC对诊断高原COPD气流阻塞均有较高的应用价值，FEV1／FVC能较好地区别阻塞性与限制性通气功能障碍，在判断气流阻塞分级时，FEV1％较好。
目的：比較FEV1佔預計值百分比(FEV1％)與FEV1／FVC比值(FEV1／FVC)對判斷高原COPD氣流阻塞的應用價值。方法：對比分析瞭海拔2 260～3 900 m地區86例COPD、32例限製性通氣功能障礙患者和30例健康人的FEV1％與FEV1／FVC。結果：COPD組FEV1％與FEV1／FVC呈正相關(r＝0.897，P＜0.01)。依FEV1％＜82％、FEV1／FVC＜77％作為判斷氣流阻塞標準，COPD組分彆為87.21％和86.05％，限製組分彆為84.38％和12.50％(P＜0.01)。作為COPD分級標準，FEV1％與FEV1／FVC的下降不一緻，Ⅱ、Ⅲ級FEV1／FVC顯著高于FEV1％(P＜0.01或P＜0.05)，Ⅰ級略低于FEV1％(P＞0.05)。結論：FEV1％和FEV1／FVC對診斷高原COPD氣流阻塞均有較高的應用價值，FEV1／FVC能較好地區彆阻塞性與限製性通氣功能障礙，在判斷氣流阻塞分級時，FEV1％較好。
목적：비교FEV1점예계치백분비(FEV1％)여FEV1／FVC비치(FEV1／FVC)대판단고원COPD기류조새적응용개치。방법：대비분석료해발2 260～3 900 m지구86례COPD、32례한제성통기공능장애환자화30례건강인적FEV1％여FEV1／FVC。결과：COPD조FEV1％여FEV1／FVC정정상관(r＝0.897，P＜0.01)。의FEV1％＜82％、FEV1／FVC＜77％작위판단기류조새표준，COPD조분별위87.21％화86.05％，한제조분별위84.38％화12.50％(P＜0.01)。작위COPD분급표준，FEV1％여FEV1／FVC적하강불일치，Ⅱ、Ⅲ급FEV1／FVC현저고우FEV1％(P＜0.01혹P＜0.05)，Ⅰ급략저우FEV1％(P＞0.05)。결론：FEV1％화FEV1／FVC대진단고원COPD기류조새균유교고적응용개치，FEV1／FVC능교호지구별조새성여한제성통기공능장애，재판단기류조새분급시，FEV1％교호。
Objective:To compare the value of the percent of the forced expiratory volume in 1 second expressed to predicted(FEV1％)with the quotient of the forced expiratory volume in 1 second to the forced vital capacity(FEV1／FVC)as a diagnostic criteria of airflow obstruction in chronic obstructive pulmonary disease (COPD)at altitudes.Methods:Results of pulmonary function test of 86 cases of COPD,32 cases of restrictive ventilative dysfunction(RVD)and 30 healthy persons at 2 260－3 900 m altitudes were analysed.Results:FEV1％ was significantly positively correlated with FEV1／FVC(r＝0.897,P＜0.01)in COPD group.By FEV1％＜82％，FEV1／FVC＜77％ as a diagnostic criteria of airflow obstruction,the positive rates were 87.21％ and 86.05％ in COPD group and 84.38％ and 12.50％(P＜0.01) in RVD group respectively.FEV1％ was not correlated with FEV1／FVC as a grading criteria of COPD.The level of FEV1／FVC was significantly higher than that of FEV1％ in Ⅱand Ⅲ degree and lower in Ⅰdegree COPD.Conclusion:FEV1％ and FEV1／FVC have important value as diagnostic criterias of airflow obstruction in COPD at altitudes.FEV1／FVC is better in distinguishing RVD from COPD.FEV1％ is better than FEV1／FVC as a grading criteria of airflow obstruction.
