CAJ | 학술논문

目的：探讨玻璃体与青光眼眼压升高的关系。方法：用玻璃体切割合并小梁切除治疗疑难青光眼及不同浓度的透明质酸酶注入兔眼玻璃体内改变玻璃体理化状态来降低眼压。结果：玻璃体切割术后随访0.5～4年，患者眼压80%控制在正常范围，自觉症状消失，眼局部充血减轻或消失，视力多保持原来状态。用药10～20～30d后，兔眼玻璃体粘稠度明显下降，眼压从2.74kPa降至1.73～1.33kPa。结论：玻璃体切割合并小梁切除及透明质酸酶兔眼玻璃体内注射法均可使眼压下降，说明玻璃体对眼内压有一定的影响，但手术及实验结果和远期疗效均有待进一步研究。
목적：탐토파리체여청광안안압승고적관계。방법：용파리체절할합병소량절제치료의난청광안급불동농도적투명질산매주입토안파리체내개변파리체이화상태래강저안압。결과：파리체절할술후수방0.5～4년，환자안압80%공제재정상범위，자각증상소실，안국부충혈감경혹소실，시력다보지원래상태。용약10～20～30d후，토안파리체점주도명현하강，안압종2.74kPa강지1.73～1.33kPa。결론：파리체절할합병소량절제급투명질산매토안파리체내주사법균가사안압하강，설명파리체대안내압유일정적영향，단수술급실험결과화원기료효균유대진일보연구。
Objective:To research the relationship between the vitreous and the high IOP.Method:Vitrectomy combined with trabeculectomy were used to deal with difficult glaucoma.Hyaluronidase with variety density was injected into rabbits' vitreous body to change the physical and chemical states in order to reduce IOP.Results:Patients with vitrectomy were followed for 0.5～4 years,80% of their IOP were controlled to normal. The symptom was disappeared. Local congestion was relived or absent. Visual acuity had no change.10～20～30 days after used drugs,the viscosity of vitreous was decreased and the IOP was decreased from 2.74kPa to 1.75～1.33kPa.Conclusion:Vitrectomy combined with trabeculectomy and injection of hyaluronidase into rabbit's vitreous can decrease IOP. This result indicate that vitreous can affect IOP, but the long-time effect of the operation and the experiment remain further researching.