CAJ | 학술논문

目的　通过观察豚鼠在窒息状态下ABR电位变化及其脑干功能的自然转归，探讨听觉通路损伤程度和临床意义。方法　听觉诱发电位仪和心电脉搏氧饱和度监测仪检测3组不同窒息时限的豚鼠的ABR各波潜伏期及波间期，氧饱和度(SO2)及心率(HR)等。结果　波Ⅴ最易受缺氧的影响，波Ⅲ次之，波Ⅰ最后消失和最早恢复。窒息时限影响脑干功能，导致1组和2组的各波潜伏期和波间期差有统计学上的意义。窒息时间超过5min30s，实验豚鼠均死亡。结论　ABR可作为窒息状态下判断脑功能及脑死亡的重要辅助指标。应争分夺秒抢救窒息并及时处理心脑的损害。
목적　통과관찰돈서재질식상태하ABR전위변화급기뇌간공능적자연전귀，탐토은각통로손상정도화림상의의。방법　은각유발전위의화심전맥박양포화도감측의검측3조불동질식시한적돈서적ABR각파잠복기급파간기，양포화도(SO2)급심솔(HR)등。결과　파Ⅴ최역수결양적영향，파Ⅲ차지，파Ⅰ최후소실화최조회복。질식시한영향뇌간공능，도치1조화2조적각파잠복기화파간기차유통계학상적의의。질식시간초과5min30s，실험돈서균사망。결론　ABR가작위질식상태하판단뇌공능급뇌사망적중요보조지표。응쟁분탈초창구질식병급시처리심뇌적손해。
Objective　To find some reasonable signs for hearing pathway injury during different apnea times in guinea pigs by using the change of the auditory brainstem response (ABR) and brainstem function. Methods　Twenty-six guinea pigs divided into 3 groups were tested with ABR audiometer and electrocaidio-pules-SO2 monitor during different apnea times. Results　Wave Ⅴ was the most easily affected in apnea, Wave Ⅲ was also easily affected, and Wave Ⅰ was less affected. The time of apnea over 330 seconds caused the death of all the experimetal guinea pigs. Conclusion　ABR may be used as an important measure to monitor the brainstem function during apnea. It is important to deal with the situation of the brain and heart as soon as possible.