CAJ | 학술논문

文中综述了昆虫对苏云金杆菌(Bt)毒素产生抗性的生化遗传机理及抗性的遗传及交叉抗性情况。昆虫对Bt毒素的抗性可能在6个环节发生，其中与毒素特异结合的受体上结合位点的改变及毒素水解过程的变化是抗性产生的两个主要环节。从现有研究结果来看，实验室及田间抗性昆虫品系对Bt毒素产生的抗性主要与昆虫中肠上皮细胞膜上Bt毒素特异结合受体的变化有关。深入研究昆虫对Bt毒素的抗性机理，将有助于建立抗性的早期监测技术、抗性治理措施，实现无公害Bt农药及转Bt基因作物的持续利用。
문중종술료곤충대소운금간균(Bt)독소산생항성적생화유전궤리급항성적유전급교차항성정황。곤충대Bt독소적항성가능재6개배절발생，기중여독소특이결합적수체상결합위점적개변급독소수해과정적변화시항성산생적량개주요배절。종현유연구결과래간，실험실급전간항성곤충품계대Bt독소산생적항성주요여곤충중장상피세포막상Bt독소특이결합수체적변화유관。심입연구곤충대Bt독소적항성궤리，장유조우건립항성적조기감측기술、항성치리조시，실현무공해Bt농약급전Bt기인작물적지속이용。
The current knowledge of biochemical and genetic mechanisms of insect resistance to Bacillus thuringiensis toxin is reviewed. Six potential steps concerning the occurrence of resistance are suggest ed. Available information on resistance inheritance and cross-resistance is provided. Binding site modifi cation and altered proteolytic processing are involved in most cases of resistance. From the available information it seems that binding site modification is the most significant resistance mechanism in the field and laboratory resistant strains. Studying the mechanism of insect resistance to Bacillus thuringiensis toxin will provide more toxin selection, wider utilization, and longer durability in integrated pest management programs that utilize Bt toxin and Bt crops.