中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
12期
1649-1650
,共2页
病毒性肝炎%血小板%凝血功能
病毒性肝炎%血小闆%凝血功能
병독성간염%혈소판%응혈공능
Virus hepatitis%Platelet parameters%Coagulation function
目的 探讨病毒性肝炎患者血小板及凝血功能指标联合检测的临床意义.方法 将310例病毒性肝炎患者分为急性肝炎组、慢性肝炎组、重度肝炎组和肝炎后肝硬化组.另外选择正常体检的健康人80例作为对照组.联合检测其血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、大型血小板比率(P-LCR)、凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血酶时间(AFTT)、纤维蛋白原浓度(Fbg).结果 慢性肝炎组、重度肝炎组和肝炎后肝硬化组的PLT、MPV和Fbg与健康对照组差异均有统计学意义(均P<0.01).PDW、P-LCR、PT、TT、APTT)与健康对照组差异均有统计学意义(均P<0.05).结论 血小板及凝血功能指标的联合检测有助于观察病毒性肝炎的病程进展程度,对于临床治疗及预后有重要意义.
目的 探討病毒性肝炎患者血小闆及凝血功能指標聯閤檢測的臨床意義.方法 將310例病毒性肝炎患者分為急性肝炎組、慢性肝炎組、重度肝炎組和肝炎後肝硬化組.另外選擇正常體檢的健康人80例作為對照組.聯閤檢測其血小闆計數(PLT)、平均血小闆體積(MPV)、血小闆分佈寬度(PDW)、大型血小闆比率(P-LCR)、凝血酶原時間(PT)、凝血酶時間(TT)、活化部分凝血酶時間(AFTT)、纖維蛋白原濃度(Fbg).結果 慢性肝炎組、重度肝炎組和肝炎後肝硬化組的PLT、MPV和Fbg與健康對照組差異均有統計學意義(均P<0.01).PDW、P-LCR、PT、TT、APTT)與健康對照組差異均有統計學意義(均P<0.05).結論 血小闆及凝血功能指標的聯閤檢測有助于觀察病毒性肝炎的病程進展程度,對于臨床治療及預後有重要意義.
목적 탐토병독성간염환자혈소판급응혈공능지표연합검측적림상의의.방법 장310례병독성간염환자분위급성간염조、만성간염조、중도간염조화간염후간경화조.령외선택정상체검적건강인80례작위대조조.연합검측기혈소판계수(PLT)、평균혈소판체적(MPV)、혈소판분포관도(PDW)、대형혈소판비솔(P-LCR)、응혈매원시간(PT)、응혈매시간(TT)、활화부분응혈매시간(AFTT)、섬유단백원농도(Fbg).결과 만성간염조、중도간염조화간염후간경화조적PLT、MPV화Fbg여건강대조조차이균유통계학의의(균P<0.01).PDW、P-LCR、PT、TT、APTT)여건강대조조차이균유통계학의의(균P<0.05).결론 혈소판급응혈공능지표적연합검측유조우관찰병독성간염적병정진전정도,대우림상치료급예후유중요의의.
Objective To investigate the clinical significance of the joint detection of platelet parameters and coagulation function markers in hepatitis patients.Methods 310 patients with viral hepatitis were divided into 4 groups:acute hepatitis group,chronic hepatitis group,serious hepatitis group and hepatocirrhosis group.The control group was the 80 healthy examination eligible people.Each group were detected platelet parameters ( PLT), mean platelet volume( MPV),.platelet distribution width( PDW),platelet large cell ratio( P-LCR), prothrombin time( PT) ,activated partial thromboplasin time (APTT ) , thrombin time ( TT) and factorl ( Fbg).Results The levels of PLT,MPV and Fbg were obviously reduced in chronic hepatitis,serious condition chronic hepatitis patients and hepatocirrhosis had significant difference compared with those in the control group (all P < 0.01).Moreover, the levels of PDW,P-LCR,PT,APTT and TT were obviously increased in the four groups compared with the control group(all P <0.05 ).Conclusion The joint detection of platelet parameters and coagulation function markers could help to observe the degree of progression of virus hepatitis,and had important clinical significance for the treatment and prognosis.
