CAJ | 학술논문

目的探讨咪喹莫特乳膏治疗尖锐湿疣的临床疗效.方法将尖锐湿疣患者90例,随机分为治疗组和对照组各45例,治疗组给予咪喹莫特乳膏外涂疣体,对照组采用α-2b干扰素乳膏外涂疣体,观察比较两组的疗效及复发率.结果治疗组的总有效率(91.1%)明显高于对照组总有效率(64.4%)(P＜0.05).治疗组的无复发38例,复发率为15.6%,对照组无复发29例,复发率为35.6%,治疗组的复发率明显低于对照组的复发率(35.6%)(P＜0.05).结论咪喹莫特疗尖锐湿疣疗效较好,复发率较低,无全身不良反应,局部反应轻,值得临床推广和应用.
목적 탐토미규막특유고치료첨예습우적림상료효.방법 장첨예습우환자90례,수궤분위치료조화대조조각45례,치료조급여미규막특유고외도우체,대조조채용α-2b간우소유고외도우체,관찰비교량조적료효급복발솔.결과 치료조적총유효솔(91.1%)명현고우대조조총유효솔(64.4%)(P＜0.05).치료조적무복발38례,복발솔위15.6%,대조조무복발29례,복발솔위35.6%,치료조적복발솔명현저우대조조적복발솔(35.6%)(P＜0.05).결론 미규막특료첨예습우료효교호,복발솔교저,무전신불량반응,국부반응경,치득림상추엄화응용.
Objective To investigate the efficacy of imiquimod cream in treatment of condyloma acuminatum. Methods 90 patients with condyloma acuminatum were randomly divided into treatment group and control group,the treatment group (45 patients) were given imiquimod cream applied externally wart,the control group was applied interferon α-2b wart cream externally,the efficacy and re]apse rate were observed and compared between two groups. Results The total effective rate in treatment group ( 91.1% ) was higher than that in control group (64. 4% ), by statistical analysis, the difference was significant (P ＜ 0.05 ). Treatment group,38 cases of non-recurrence,the recurrence rate was 15. 6% ,in the eontrol group had no recurrence in 29 cases,the recurrence rate was 35.6%, the recurrence rate of the treatment group was significantly lower than control group, the difference was significant ( P ＜ 0.05 ). Conclusion The efficacy of imiquimod treatment had lower recurrence rate and no systemic adverse reactions, local reactions was light, worthy to be popularized and applied.