CAJ | 학술논문

目的描述迟发性运动障碍(TD)患者异常不自主运动的状况和特征,分析TD发生可能的相关因素.方法共入组TD患者140例,采用阳性和阴性症状量表(PANSS)评定精神症状,采用Simpson迟发性运动障碍专用量表、异常不自主运动评定量表(AIMS)系统评估TD的严重程度及发生频率.结果在140例TD患者的8类不同部位的异常运动中,上、下肢体和舌部的舞蹈样动作发生率最高(均大于80%),其中上肢的异常不自主运动的发生比例高达90%,脸部、颌异常运动的发生率只有30%左右.结论在TD患者中,四肢末端和舌部的异常不自主运动最为频发,典型的口-舌-颊三联征并不常见.
목적 묘술지발성운동장애(TD)환자이상불자주운동적상황화특정,분석TD발생가능적상관인소.방법 공입조TD환자140례,채용양성화음성증상량표(PANSS)평정정신증상,채용Simpson지발성운동장애전용량표、이상불자주운동평정량표(AIMS)계통평고TD적엄중정도급발생빈솔.결과 재140례TD환자적8류불동부위적이상운동중,상、하지체화설부적무도양동작발생솔최고(균대우80%),기중상지적이상불자주운동적발생비례고체90%,검부、합이상운동적발생솔지유30%좌우.결론 재TD환자중,사지말단화설부적이상불자주운동최위빈발,전형적구-설-협삼련정병불상견.
Objective To investigate the clinical features and frequencies of abnormal involuntary movement symptoms in schizophrenic patients with Tardive Dyskinesia(TD). Methods To evaluate severity and frequency of dyskinesia movement in schizophrenic patients with TD (n=140) by the Abnormal Involuntary Movement Scale (AIMS) and the Simpson-Angus Extrapyramidal Sign Scale,to assess the psychophathology with Positive and Negative Symptom Scale (PANSS). Results Among 140 patients with TD recruited in the present study,the abnormal involuntary movements of extremities (upper limb: 92.6 %; lower limb : 80.00%) and tongue (89.2%)were the most significant manifestations in the AIMS, oro-buccal-lingual-facial (oroiacial) dyskinesia was not a common manifestation (the rate was 30 %). Conclusion Abnormal involuntary movements in the extremi-ties and tongue in patients with TD are the most manifestation. On the contrary, oro-buccal-lingual-facial (oro-facial) dyskinesia is not common clinical features.