中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2011年
8期
668-671
,共4页
马千里%龙舟%张巧%黄赞胜%吴颖%王长征
馬韆裏%龍舟%張巧%黃讚勝%吳穎%王長徵
마천리%룡주%장교%황찬성%오영%왕장정
咳嗽,慢性%咳嗽激发试验
咳嗽,慢性%咳嗽激髮試驗
해수,만성%해수격발시험
Cough,chronic%Cough reflex sensitivity test
目的 初步观察咳嗽激发试验在不同性别、病程、病因的慢性咳嗽患者中的差异,以期为进一步评价咳嗽激发试验的临床意义及对临床诊疗慢性咳嗽提供启迪和帮助.方法 选择进行了咳嗽激发试验并最终确诊为上气道咳嗽综合征(UACS)、咳嗽变异性哮喘(CVA)、胃食管反流性咳嗽(GERC)的慢性咳嗽患者108例,分析咳嗽激发试验在不同病因、病程、性别的慢性咳嗽患者间的差异.结果 108例慢性咳嗽患者中UACS 76例,CVA 19例,GERC 13例.咳嗽敏感性阈值的对数(lgC5)女性患者(1.80)显著低于男性(2.40,P<0.05);病程≥12个月患者lgC5(1.80)显著低于病程<12个月的患者(2.40,P<0.05);不同病因患者lgC5存在显著差异,其中GERC患者的lgC5(1.49)显著低于CVA(2.40,P<0.05)和UACS(2.40,P<0.05)患者.结论 不同病因、病程、性别的慢性咳嗽患者咳嗽敏感性均存在差异,咳嗽激发试验在慢性咳嗽病因诊断中具有重要价值.
目的 初步觀察咳嗽激髮試驗在不同性彆、病程、病因的慢性咳嗽患者中的差異,以期為進一步評價咳嗽激髮試驗的臨床意義及對臨床診療慢性咳嗽提供啟迪和幫助.方法 選擇進行瞭咳嗽激髮試驗併最終確診為上氣道咳嗽綜閤徵(UACS)、咳嗽變異性哮喘(CVA)、胃食管反流性咳嗽(GERC)的慢性咳嗽患者108例,分析咳嗽激髮試驗在不同病因、病程、性彆的慢性咳嗽患者間的差異.結果 108例慢性咳嗽患者中UACS 76例,CVA 19例,GERC 13例.咳嗽敏感性閾值的對數(lgC5)女性患者(1.80)顯著低于男性(2.40,P<0.05);病程≥12箇月患者lgC5(1.80)顯著低于病程<12箇月的患者(2.40,P<0.05);不同病因患者lgC5存在顯著差異,其中GERC患者的lgC5(1.49)顯著低于CVA(2.40,P<0.05)和UACS(2.40,P<0.05)患者.結論 不同病因、病程、性彆的慢性咳嗽患者咳嗽敏感性均存在差異,咳嗽激髮試驗在慢性咳嗽病因診斷中具有重要價值.
목적 초보관찰해수격발시험재불동성별、병정、병인적만성해수환자중적차이,이기위진일보평개해수격발시험적림상의의급대림상진료만성해수제공계적화방조.방법 선택진행료해수격발시험병최종학진위상기도해수종합정(UACS)、해수변이성효천(CVA)、위식관반류성해수(GERC)적만성해수환자108례,분석해수격발시험재불동병인、병정、성별적만성해수환자간적차이.결과 108례만성해수환자중UACS 76례,CVA 19례,GERC 13례.해수민감성역치적대수(lgC5)녀성환자(1.80)현저저우남성(2.40,P<0.05);병정≥12개월환자lgC5(1.80)현저저우병정<12개월적환자(2.40,P<0.05);불동병인환자lgC5존재현저차이,기중GERC환자적lgC5(1.49)현저저우CVA(2.40,P<0.05)화UACS(2.40,P<0.05)환자.결론 불동병인、병정、성별적만성해수환자해수민감성균존재차이,해수격발시험재만성해수병인진단중구유중요개치.
Objective Preliminary study of the cough reflex sensitivity test in chronic cough patients with different gender,disease duration and causes to evaluate the clinical diagnostic significance of the test and further provide some information for the treatment of chronic cough.Methods Totally 108 chronic cough patients in our hospital were enrolled in the study with the final diagnosis of upper airway cough syndrome(UACS),cough variant asthma(CVA)and gastroesophageal reflux cough(GERC).They all went through the cough reflex sensitivity test and the retrospective analysis of the results was made.Results In 108 patients with chronic cough(76 UACS,19 CVA and 13 GERC),lgC5 was significantly slower in the female(1.80)than the male(2.40,P<0.05)and in the patients with cough duration over 12 months(1.80)than those with cough duration under 12 months(2.40,P<0.05).Cough sensitivity in patients with different causes was significantly different(P<0.05)with lower lgC5 in GERC patients(1.49)than CVA (2.40,P<0.05)and UACS(2.40,P<0.05)patients.Conclusion Cough sensitivity is different in chronic cough patients with different gender,disease duration and causes.Cough reflex sensitivity test is of great value in the etiology diagnosis of chronic cough.
