中华器官移植杂志
中華器官移植雜誌
중화기관이식잡지
CHINESE JOURNAL OF ORGAN TRANSPLANTATION
2011年
6期
330-333
,共4页
郑树森%汪恺%徐骁%凌琪%陈峻%张珉%王伟林%吴健%刘治坤%郭海军
鄭樹森%汪愷%徐驍%凌琪%陳峻%張珉%王偉林%吳健%劉治坤%郭海軍
정수삼%왕개%서효%릉기%진준%장민%왕위림%오건%류치곤%곽해군
杭州标准%肝细胞癌%活体供者%肝移植%预后
杭州標準%肝細胞癌%活體供者%肝移植%預後
항주표준%간세포암%활체공자%간이식%예후
Hangzhou Criteria%Hepatocellular carcinoma%Living donor%Liver transplantation%Prognosis
目的 探讨肝移植治疗肝癌的受者选择杭州标准在亲属活体供肝移植中的应用价值,及其对术后存活的影响.方法 回顾分析43例亲属活体供肝移植受者的临床资料.按照是否符合米兰标准、Up-To-Seven标准及杭州标准将受者分组,比较各组纳入受者的例数、术后总体存活率及无瘤存活率.结果 符合杭州标准的受者例数比米兰标准增加了61.5 %(8/13),比Up-to-Seven标准增加了23.5 %(4/17).符合米兰标准的受者(13例)术后1、3年总体存活率和无瘤存活率分别为100 %、80.0 %和84.6 %、84.6 %;符合Up-to-Seven标准的受者(17例)术后1、3年总体存活率和无瘤存活率分别为100 %、75.2 %和87.5 %、81.2 %;符合杭州标准的受者(21例)术后1、3年总体存活率和无瘤存活率分别为100 %、80.0 %和89.5 %、84.2 %.3组间总体存活率和无瘤存活率的比较,差异均无统计学意义(P＞0.05).结论 杭州标准能将更多的肝癌患者纳入肝移植,且不影响术后总体存活率和无瘤存活率,是筛选肝癌患者接受亲属活体肝移植的有效标准.
目的 探討肝移植治療肝癌的受者選擇杭州標準在親屬活體供肝移植中的應用價值,及其對術後存活的影響.方法 迴顧分析43例親屬活體供肝移植受者的臨床資料.按照是否符閤米蘭標準、Up-To-Seven標準及杭州標準將受者分組,比較各組納入受者的例數、術後總體存活率及無瘤存活率.結果 符閤杭州標準的受者例數比米蘭標準增加瞭61.5 %(8/13),比Up-to-Seven標準增加瞭23.5 %(4/17).符閤米蘭標準的受者(13例)術後1、3年總體存活率和無瘤存活率分彆為100 %、80.0 %和84.6 %、84.6 %;符閤Up-to-Seven標準的受者(17例)術後1、3年總體存活率和無瘤存活率分彆為100 %、75.2 %和87.5 %、81.2 %;符閤杭州標準的受者(21例)術後1、3年總體存活率和無瘤存活率分彆為100 %、80.0 %和89.5 %、84.2 %.3組間總體存活率和無瘤存活率的比較,差異均無統計學意義(P＞0.05).結論 杭州標準能將更多的肝癌患者納入肝移植,且不影響術後總體存活率和無瘤存活率,是篩選肝癌患者接受親屬活體肝移植的有效標準.
목적 탐토간이식치료간암적수자선택항주표준재친속활체공간이식중적응용개치,급기대술후존활적영향.방법 회고분석43례친속활체공간이식수자적림상자료.안조시부부합미란표준、Up-To-Seven표준급항주표준장수자분조,비교각조납입수자적례수、술후총체존활솔급무류존활솔.결과 부합항주표준적수자례수비미란표준증가료61.5 %(8/13),비Up-to-Seven표준증가료23.5 %(4/17).부합미란표준적수자(13례)술후1、3년총체존활솔화무류존활솔분별위100 %、80.0 %화84.6 %、84.6 %;부합Up-to-Seven표준적수자(17례)술후1、3년총체존활솔화무류존활솔분별위100 %、75.2 %화87.5 %、81.2 %;부합항주표준적수자(21례)술후1、3년총체존활솔화무류존활솔분별위100 %、80.0 %화89.5 %、84.2 %.3조간총체존활솔화무류존활솔적비교,차이균무통계학의의(P＞0.05).결론 항주표준능장경다적간암환자납입간이식,차불영향술후총체존활솔화무류존활솔,시사선간암환자접수친속활체간이식적유효표준.
Objective To investigate the clinical value of Hangzhou Criteria in selection of patients with hepatocellular carcinoma(HCC)for living donor liver transplantation(LDLT)and their effects on recipient's post-transplant survival.Methods A retrospective analysis was conducted on 43 patients with HCC who underwent LDLT in our center.All of the recipients were classified into subgroups according to Milan Criteria,Up-to-Seven Criteria and Hangzhou Criteria,and post-transplant total survival rate and tumor-free survival rate were compared among the criteria.Results The number of patients within Hangzhou Criteria was 61.5 %(8/13)more than that within Milan Criteria and 23.5 %(4/17)more than that within Up-to-Seven Criteria.The 1-,and 3-years total survival rate and tumor-free survival rate of the recipients within Milan Criteria(n=13)were 100 %,80.0 % and 84.6 %,84.6 %,those of the recipients within Up-to-Seven Criteria(n=17)were 100 %,75.2 % and 87.5 %,81.2 %,and those of the recipients within Hangzhou Criteria(n=21)were 100 %,80.0 % and 89.5 %,84.2 %,respectively.There was no significant difference among the three criteria in total survival rate and tumor-free survival rate(P>0.05).Conclusion Hangzhou Criteria further enrolled more liver transplantation candidates without decline of total survival rate and tumor-free survival.It is a more effective selection of HCC recipients for LDLT.
