中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2009年
4期
117-119
,共3页
普贝生%米索前列醇%缩宫素%Bishop评分
普貝生%米索前列醇%縮宮素%Bishop評分
보패생%미색전렬순%축궁소%Bishop평분
Dinoprostone suppositories%Misoprostol%Oxytocin%Bishop score
目的 观察普贝生、米索前列醇、缩宫素三种促进官颈成熟药物的有效性和安全性.方法 采用随机对照研究方法,将180例初产妇分为3组,A组:普贝生;B组:小剂量米索前列醇组;C组:缩宫素组.比较三组用药前、后4、8、12 h官颈Bishop评分,用药后分娩情况、胎儿窘迫及新生儿窒息的发生率.结果 A、B、C三组的有效率分别为88.3%、85.0%、35.0%;用药后剖宫产率分别为21.7%、25.0%、60.0%.A,B组分别与C组比较差异有统计学意义(P＜0.05).结论 普贝生及米索前列醇均是安全、有效的,临床应用成功率高;缩宫素则疗效欠佳.
目的 觀察普貝生、米索前列醇、縮宮素三種促進官頸成熟藥物的有效性和安全性.方法 採用隨機對照研究方法,將180例初產婦分為3組,A組:普貝生;B組:小劑量米索前列醇組;C組:縮宮素組.比較三組用藥前、後4、8、12 h官頸Bishop評分,用藥後分娩情況、胎兒窘迫及新生兒窒息的髮生率.結果 A、B、C三組的有效率分彆為88.3%、85.0%、35.0%;用藥後剖宮產率分彆為21.7%、25.0%、60.0%.A,B組分彆與C組比較差異有統計學意義(P＜0.05).結論 普貝生及米索前列醇均是安全、有效的,臨床應用成功率高;縮宮素則療效欠佳.
목적 관찰보패생、미색전렬순、축궁소삼충촉진관경성숙약물적유효성화안전성.방법 채용수궤대조연구방법,장180례초산부분위3조,A조:보패생;B조:소제량미색전렬순조;C조:축궁소조.비교삼조용약전、후4、8、12 h관경Bishop평분,용약후분면정황、태인군박급신생인질식적발생솔.결과 A、B、C삼조적유효솔분별위88.3%、85.0%、35.0%;용약후부궁산솔분별위21.7%、25.0%、60.0%.A,B조분별여C조비교차이유통계학의의(P＜0.05).결론 보패생급미색전렬순균시안전、유효적,림상응용성공솔고;축궁소칙료효흠가.
Objective To observe the efficacy and safety of three drugs(dinoprostone suppositories,misopmstol and oxytocin) to promote cervieal ripening.Methods A randomized control study method was used.The 180 primipara was divided into 3 groups.Group A:dinoprostone suppositories,Group B:low-dose misoprostol,Group C:oxytocin.The maternal cervical Bishop score of three drugs being used before and after 4,8,12 h was compared between the three groups,as well as the labor situation,the rate of fetal distress and neonatal asphyxia after the drugs.Results The effective rates of groups A,B,C were 88.3%,85.0%,35.0%.The cesarean section rates of three groups were 21.7%,25.0%,60.0%.There was significantly different between groups A,B with group C(P＜0.05).Conclusion Dinoprostone suppositories and misoprostol were safe and effective,and they had a high success rate of clinical application.Then Oxytocin was ill effect.
