CAJ | 학술논문

目的观察同活度、同数量~(125)I粒子单平面布源的剂量分布.方法利用计算机三维治疗计划系统(TPS)模拟9颗2.96×10~7Bq(贝克)~(125)I粒子9种分布模式,求出60、80、130、145、200Gy剂量分布曲线及曲线包含的面积、长径、短径.结果粒子不同分布时相同等剂量曲线包含的面积、长径、短径存在差异.60、80、130、145、200Gy等剂量曲线内面积最大的粒子排列分别为:X1.5Y1.5、X1Y1.5、X1Y1(2)1.5、X1Y1、X1Y1(2)0.5,对应的面积分别为:1641.91、1166.42、791.09、718.27、474.63 mm~2.结论同活度、同数量~(125)I粒子的不同布源方式直接影响剂量分布.同一剂量曲线内面积最大时的粒子排列剂量分布较均匀,靶区内无剂量学冷点,可能会有较好疗效.
목적 관찰동활도、동수량~(125)I입자단평면포원적제량분포.방법 이용계산궤삼유치료계화계통(TPS)모의9과2.96×10~7Bq(패극)~(125)I입자9충분포모식,구출60、80、130、145、200Gy제량분포곡선급곡선포함적면적、장경、단경.결과 입자불동분포시상동등제량곡선포함적면적、장경、단경존재차이.60、80、130、145、200Gy등제량곡선내면적최대적입자배렬분별위:X1.5Y1.5、X1Y1.5、X1Y1(2)1.5、X1Y1、X1Y1(2)0.5,대응적면적분별위:1641.91、1166.42、791.09、718.27、474.63 mm~2.결론 동활도、동수량~(125)I입자적불동포원방식직접영향제량분포.동일제량곡선내면적최대시적입자배렬제량분포교균균,파구내무제량학랭점,가능회유교호료효.
Objective To study the dosimetrie effect of different ~(125)I seeds arrangements when implanted at the same number and activity (2.96×10~7 Bq) in a plane. Methods Nine different arrangements of ~(125)I seed plane implantation were established with the three-dimensional treatment planning system (TPS) and the isodose curves of 60, 80, 130, 145 and 200 Gy were figured out. The areas and radius in these isodose curves were calculated with the professional image analysis software. Results The areas and radius in the same isedose curves were dissimilar when the arrangement was different. The arrangements which had the maxima area in the 60, 80, 130, 145 and 200 Gy isodose curves were X1.5Y1.5, X1Y1.5, X1Y1(2)1.5, X1Y1, X1Y1(2) 0.5 with the area of 1641.91, 1166.42,791.09,718.27,474.63 mm~2 respectively. The seeds arrangement with the maximum area in the same isodose curve had a better dose distribution and there were no cold spots in the target. Conclusion The dose and therapeutic effect was influenced significantly by the arrangemeut of the seeds even the number and activity were equal.