CAJ | 학술논문

目的探讨宫颈电环锥切术(LEEP)对宫颈上皮内瘤变(CIN)患者的生育能力及妊娠结局的影响.方法 2009年1月-2011年8月于我院因CIN住院治疗的患者20例,给予LEEP治疗,作为观察组,同时随机抽取我院孕前门诊同期内就诊的无妇科手术史的20例健康孕妇,作为对照组,观察妊娠情况及妊娠结局.结果观察组患者的妊娠率为85％(17/20),对照组健康孕妇的妊娠率为90％(8/20),两组妊娠率比较差异无显著性(P＞0.05).观察组剖宫产率显著高于对照组(P＜0.05),两组患者流产发生率、早产发生率、胎膜早破发生率以及小于胎龄儿的发生率比较,差异无显著性(P＞0.05),两组患者中无新生儿死亡发生.结论 LEEP对CIN患者的生育能力无明显影响,不增加流产率、早产率、胎膜早破及小于胎龄儿发生率.
목적 탐토궁경전배추절술(LEEP)대궁경상피내류변(CIN)환자적생육능력급임신결국적영향.방법 2009년1월-2011년8월우아원인CIN주원치료적환자20례,급여LEEP치료,작위관찰조,동시수궤추취아원잉전문진동기내취진적무부과수술사적20례건강잉부,작위대조조,관찰임신정황급임신결국.결과 관찰조환자적임신솔위85％(17/20),대조조건강잉부적임신솔위90％(8/20),량조임신솔비교차이무현저성(P＞0.05).관찰조부궁산솔현저고우대조조(P＜0.05),량조환자유산발생솔、조산발생솔、태막조파발생솔이급소우태령인적발생솔비교,차이무현저성(P＞0.05),량조환자중무신생인사망발생.결론 LEEP대CIN환자적생육능력무명현영향,불증가유산솔、조산솔、태막조파급소우태령인발생솔.
Objective To investigate the effects of cervical loop electrosurgical excision procedure (LEEP) to fertility and pregnancy outcome of patients with cervical intraepithelial neoplasia (CIN).Methods 20 inpatients of CIN from January 2009 to August 2011 were given the LEEP treatment,as the observation group,while other 20 healthy pregnant women randomly selected within the same period of the pregnancy out-patient hospital treatment without history of gynecological surgery,were observed as the control group,the observed pregnancy rate and pregnancy outcome were examined.Results The pregnancy rate of the observation group of 20 patients was 85％ (17/20),preguancy rate was 90％ (18/20) in the control group,there was no significant difference (P＞ 0.05).Cesarean section rate of the observation group was significantly higher than that in the control group (P＜0.05),and there was also no significant difference in abortion incidence,incidence of preterm premature,rupture of membranes incidence and the incidence of small for gestational age (SGA) children in two groups(P＞0.05),no neonatal deaths occurred in the patients of two groups.Conclusion LEEP has no significant effect on the fertility of the CIN patients,without increasing the abortion rate,the rate of preterm birth,premature rupture of membranes,and incidence of SGA children.