CAJ | 학술논문

目的比较快速旋转调强与固定野动态调强放疗技术在局部进展期鼻咽癌治疗中的剂量学差异.方法选取10例局部进展期鼻咽癌患者,采用两种治疗技术设计同步推量调强放疗计划.在满足95%计划靶体积达60 Gy情况下,比较两种计划的剂量体积直方图、靶区和危及器官剂量、机器跳数、治疗时间.结果快速旋转调强与固定野动态调强放疗计划在局部进展期鼻咽癌治疗剂量学上无差异.快速旋转调强计划比固定野动态调强放疗技术的靶区平均剂量略升高,最大、最小剂量无差异,脑干、下颌骨及整个治疗区域正常组织受量降低,腮腺、视神经、晶体等危及器官剂量无差异.快速旋转调强计划比固定野动态调强放疗计划的总机器跳数平均减少了57%(589.5 MU:1381.0 MU),每次治疗时间平均减少了70%(2.33 min:7.82 min).结论两种放疗技术的治疗计划剂量分布基本一致,均能满足临床治疗需要.快速旋转调强放疗每次治疗时间明显缩短,其总机器跳数的降低减少了正常组织受照剂量.
목적 비교쾌속선전조강여고정야동태조강방료기술재국부진전기비인암치료중적제량학차이.방법 선취10례국부진전기비인암환자,채용량충치료기술설계동보추량조강방료계화.재만족95%계화파체적체60 Gy정황하,비교량충계화적제량체적직방도、파구화위급기관제량、궤기도수、치료시간.결과 쾌속선전조강여고정야동태조강방료계화재국부진전기비인암치료제량학상무차이.쾌속선전조강계화비고정야동태조강방료기술적파구평균제량략승고,최대、최소제량무차이,뇌간、하합골급정개치료구역정상조직수량강저,시선、시신경、정체등위급기관제량무차이.쾌속선전조강계화비고정야동태조강방료계화적총궤기도수평균감소료57%(589.5 MU:1381.0 MU),매차치료시간평균감소료70%(2.33 min:7.82 min).결론 량충방료기술적치료계화제량분포기본일치,균능만족림상치료수요.쾌속선전조강방료매차치료시간명현축단,기총궤기도수적강저감소료정상조직수조제량.
Objective To compare the dosimetric difference of RapidArc and fixed gantry angle dynamic IMRT (dIMRT) for loco-regionally advanced nasopharyngeal carcinoma.Methods Ten previously treated patients with loco-regionally advanced nasopharyngeal carcinoma were replanned with RapidArc and dIMRT, respectively.The prescription dose was GTV 70 Gy/33 f and PTV 60 Gy/33 f.All plans met the requirement:95% of PTV was covered by 60 Gy.Dose-volume histogram data, isodose distribution, monitor units,and treatment time were compared.Results Dose distribution has no significant difference between the two techniques.RapidArc reduced the dose of the brainstem, mandible, and other normal tissues compared with dIMRT.Mean monitor units were 589.5 and 1381.0 for RapidArc and dIMRT (reduced by 57% relatively).Mean treatment time was 2.33 min and 7.82 min for RapidArc and dIMRT (reduced by 70% relatively).Conclusions Compared with dIMRT, RapidArc achieves equal target coverage and OAR sparing while using fewer monitor units and less time during radiotherapy for patient with loco-regionally advanced nasopharyngeal carcinoma.