CAJ | 학술논문

目的评价注射用血凝酶用于治疗拔牙术后顽固性出血的临床效果.方法选择2006年7月-2009年7月中山大学附属口腔医院收治的32例诊断为拔牙术后顽固性出血患者,按随机数字表分为试验组和对照组,各16例.局部常规处理后,试验组给予注射用血凝酶2 U肌注,对照组给予止血敏0.5g肌注,观察局部止血情况.结果两实验组有效15例,无效1例,止血有效率为93.75%;对照组有效9例,无效7例,止血有效率为56.23%.两组有效率比较差异有显著性(P<0.05).结论注射用血凝酶在治疗拔牙术后顽固性出血方面有良好的止血效果.
목적 평개주사용혈응매용우치료발아술후완고성출혈적림상효과.방법 선택2006년7월-2009년7월중산대학부속구강의원수치적32례진단위발아술후완고성출혈환자,안수궤수자표분위시험조화대조조,각16례.국부상규처리후,시험조급여주사용혈응매2 U기주,대조조급여지혈민0.5g기주,관찰국부지혈정황.결과 량실험조유효15례,무효1례,지혈유효솔위93.75%;대조조유효9례,무효7례,지혈유효솔위56.23%.량조유효솔비교차이유현저성(P<0.05).결론주사용혈응매재치료발아술후완고성출혈방면유량호적지혈효과.
Objective To assess the efficacy of hemocoagulase atrox for injection in the treatment of post-extraction refractory bleeding. Methods 32 patients aged 21 to 72 (11 males and 21 females, mean age 42 years) who had been diagnosed as post-extraction refractory bleeding during July 2006 to July 2009 in Sun Yat-Sen university school of stomatology were randomly to receive 2U of hemocoagulase atrox for injection (16 patients, study group), or 0.5 g of etamsvlatum (16 patients, control group). The local hemostatic status was observed and the hemostatic effect was compared between the two groups with chi square test.Results There was a statistical significance between the study group and the control group in the effective rate (93.8% vs. 56.3%; x2= 6,P<0.05). Conclusions Hemocoagulase atrox for injection has a better hemostatic effect on post-extraction refractory bleeding.