CAJ | 학술논문

The main part of glucocorticoid in human body is cortisol. The Change regularity of the adrenal cortex function of pre-and postoperative children with pyogenic infections can be understood by measuring plasma cortisol level. Radioimmunoassay(RIA)was employed in the determination in 22 pyogenic infection cases and 17 non-infections. The infection cases were divided into two groups, one was celiac viseeral and general infections in which cortisol level was high, the secretion of glucocorticold was increased and cortisol coacentration raised in blood. The mean value and standad deviation was 38.61±20.19 ug/dl. And the other was superficial soft. tissue infections, where cortisol was not, or just slightly, increased (8.33±5.19 ug/dl)Cortisol was re-assyed 3-7days after the removal of the infections and pus drainage. In the former group, the cortisol level was found evidently decreased(12.65±7.20 ug/dl)and had statistically significant difference before and after operation(P＜0.01), but not the latter group(P＞0.05). Different reactions of cortex function in various pyogenic periods was discussed.