中华小儿外科杂志
中華小兒外科雜誌
중화소인외과잡지
CHINESE JOURNAL OF PEDIATRIC SURGERY
1997年
2期
79-81
,共3页
陈宗雄%杨筱菊%张卉萍%林富林
陳宗雄%楊篠菊%張卉萍%林富林
진종웅%양소국%장훼평%림부림
先天性膈疝%新生儿外科%尸体解剖%病理改变
先天性膈疝%新生兒外科%尸體解剖%病理改變
선천성격산%신생인외과%시체해부%병리개변
Congenital diaphragmatic hernia%Neonatal surgery%Autopsy%Pathological change
目的:研究新生儿先天性膈疝(CDH)的死亡原因及病理变化特点.方法:应用大体观察,各重要器官作组织切片后镜检,结合临床资料对1 080例死亡新生儿进行尸检分析.结果:检出CDH11例(1%).其中1987~1996年内约300例中检出9例.左8例,右3例,均为巨型Bochdalek疝.疝入器官多寡不一.患侧伴或不伴有对侧肺明显受压,萎陷,心纵隔移位5例.各重要脏器严重淤血.此外,伴有心血管畸形5例,左肺上下叶倒置1例,肝左叶扭转伴胆囊缺如1例,双侧并指并趾畸形1例.结论:近年来新生儿CDH检出率有所增加,不容忽视.多发生于左侧.多伴有其它器官畸形,但未发现明显遗传倾向.肺受压萎缩及心纵隔移位为主要死亡原因.
目的:研究新生兒先天性膈疝(CDH)的死亡原因及病理變化特點.方法:應用大體觀察,各重要器官作組織切片後鏡檢,結閤臨床資料對1 080例死亡新生兒進行尸檢分析.結果:檢齣CDH11例(1%).其中1987~1996年內約300例中檢齣9例.左8例,右3例,均為巨型Bochdalek疝.疝入器官多寡不一.患側伴或不伴有對側肺明顯受壓,萎陷,心縱隔移位5例.各重要髒器嚴重淤血.此外,伴有心血管畸形5例,左肺上下葉倒置1例,肝左葉扭轉伴膽囊缺如1例,雙側併指併趾畸形1例.結論:近年來新生兒CDH檢齣率有所增加,不容忽視.多髮生于左側.多伴有其它器官畸形,但未髮現明顯遺傳傾嚮.肺受壓萎縮及心縱隔移位為主要死亡原因.
목적:연구신생인선천성격산(CDH)적사망원인급병리변화특점.방법:응용대체관찰,각중요기관작조직절편후경검,결합림상자료대1 080례사망신생인진행시검분석.결과:검출CDH11례(1%).기중1987~1996년내약300례중검출9례.좌8례,우3례,균위거형Bochdalek산.산입기관다과불일.환측반혹불반유대측폐명현수압,위함,심종격이위5례.각중요장기엄중어혈.차외,반유심혈관기형5례,좌폐상하협도치1례,간좌협뉴전반담낭결여1례,쌍측병지병지기형1례.결론:근년래신생인CDH검출솔유소증가,불용홀시.다발생우좌측.다반유기타기관기형,단미발현명현유전경향.폐수압위축급심종격이위위주요사망원인.
Objective:To discuss the cause of death and the pathological changes of congenital diaphragmatic hernia(CDH).Methods:Autopsies were performed on 1 080 neonatal cadavers.Results:Eleven cases of CDH were found.Nine of the 11 cases were found in recent 300 autopsies (from 1987 to 1996).In all the 11 cases a large Bochdalek hernia(left 8 and right 3)was found.Herniated organs were different in each cadaver,but in all cadavers the lungs of the affected side were distinctly compressed and underdeveloped with or without involving the opposite side.Five cases had deviation of mediastinum.All important organs were seriously congested.In addition,5 cases were accompanied with cardiovascular deformity,1 case with transposition of left upper and lower pulmonary lobes,1 case with torsion of left hepatic lobe and gallbladder agenesis,and 1 case with ploy-dactylion.Conclusions;The increasing incidence of CDH in neonatal cadavers in recent years must be aware of.CDH mainly occours in left side.Most cases accompany with other deformities,but the hereditary trend has not been found.Serious compression of lungs and deviation of cardiomediastinum are the main factors causing death.