CAJ | 학술논문

目的探讨尿毒清颗粒与海昆肾喜胶囊治疗老年早期肾功能不全的疗效. 方法 65例老年早期肾功能不全患者随机分为海昆肾喜胶囊组(甲组)31例,尿毒清颗粒组(乙组)34例,均治疗12周,比较用药前后患者肾功能的变化及临床效果. 结果全部患者均完成12周疗程,甲组,显效3例,有效13例,总有效率为51.6%.乙组,显效7例,有效12例,总有效率55.9%,治疗结束后,两组患者的血肌酐、尿素氮均较治疗前明显降低,差异有统计学意义(P<0.01).乙组较甲组效果略好,但无统计学意义(P>0.05). 结论海昆肾喜胶囊和尿毒清颗粒均能有效降低血肌酐和尿素氮,改善肾功能,疗效确切,是治疗老年早期肾功能不全,安全有效的药物.
목적 탐토뇨독청과립여해곤신희효낭치료노년조기신공능불전적료효. 방법 65례노년조기신공능불전환자수궤분위해곤신희효낭조(갑조)31례,뇨독청과립조(을조)34례,균치료12주,비교용약전후환자신공능적변화급림상효과. 결과 전부환자균완성12주료정,갑조,현효3례,유효13례,총유효솔위51.6%.을조,현효7례,유효12례,총유효솔55.9%,치료결속후,량조환자적혈기항、뇨소담균교치료전명현강저,차이유통계학의의(P<0.01).을조교갑조효과략호,단무통계학의의(P>0.05). 결론 해곤신희효낭화뇨독청과립균능유효강저혈기항화뇨소담,개선신공능,료효학절,시치료노년조기신공능불전,안전유효적약물.
Objective To evaluate the clinical efficacy and safety of Niaoduqing particles and Haikunshenxi capsule on chronic renal failure(CRF)at early stage in aged patients.Methods 65 CRF patients were randomly divided into two groups:34 case were treated with Niaoduqing particles and 31 cases were treated with Haikunshenxi capsule for 12 weeks.The clinical manifestations and renal function before and after treatment were compared.Results The blood urea nitrogen(BUN)and serum creatinine(Scr)significantly reduced after the treatment in Niaoduqing particles group and Haikunshenxi capsule group(P<0.01).In the 31 patients of Haikunshenxi capsule group,it is sisnificantly effective in 3 cases:effective in 13 cases,and total effective rate is 51.6%.In the 34 patients of Niaoduqing particles group.it is significantly effective in 7 cases;effective in 12 cases and total effective rate is 55.9%.The effect of Niaoduqing particles group is better than Haikunshenxi capsule particles group,but there is not statistically significant(P>0.05).Conclusion Niaoduqing particles and Haikunshenxi capsule can decrease Scr and Bun and improve renal function in the treatment of chronic renal failure at early stage in aged patients.