CAJ | 학술논문

目的：探讨铁蛋白和免疫功能的关系。方法：放免方法测定胃癌病人手术前后血清铁蛋白IgG、IgM、C3及淋巴细胞转化试验(LTT)和用药前后LTT、铁蛋白的值。结果：胃癌病人术后血清铁蛋白、IgG、IgA、IgM及C3均有升高(P<0.05)，而LTT显著低于正常对照组。左旋咪唑应用后LTT升高，铁蛋白下降，有统计学意义。结论：铁蛋白是一种免疫抑制因子。可以指示机体免疫功能状态。
목적：탐토철단백화면역공능적관계。방법：방면방법측정위암병인수술전후혈청철단백IgG、IgM、C3급림파세포전화시험(LTT)화용약전후LTT、철단백적치。결과：위암병인술후혈청철단백、IgG、IgA、IgM급C3균유승고(P<0.05)，이LTT현저저우정상대조조。좌선미서응용후LTT승고，철단백하강，유통계학의의。결론：철단백시일충면역억제인자。가이지시궤체면역공능상태。
Objective: To investigate the relation of serum ferritin to immunologic function. Method: Serum ferritin, IgG, IgA, IgM, C3 and LTT were examinated by radio immunoassay in the patient with gastric cancer before and after operation. Result: Postoperation serum ferritin, IgG, IgA, IgM and C3 in the patient with gastric cancer were higher and LTT was lower and the difference between the two groups was of stastically significance. Tetramisolum could significantly increase level of LTT and decrease level of serum ferritin. Conclusion: Ferritin is an immunosuppressive factor and show the immune function of the human body.