中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2009年
1期
22-24
,共3页
陈红兵%郑海涛%姜立新%郭吉田%吕忠船
陳紅兵%鄭海濤%薑立新%郭吉田%呂忠船
진홍병%정해도%강립신%곽길전%려충선
甲状腺转移癌%诊断%治疗%预后
甲狀腺轉移癌%診斷%治療%預後
갑상선전이암%진단%치료%예후
Secondary thyroid neoplasm%Diagnosis%Treatment%Prognosis
目的 探讨甲状腺转移癌的临床发病特点、诊断、治疗及预后分析.方法 回顾性分析83例甲状腺转移癌病例.结果 83例患者中,男性39例,女性39例,性别不明5例;年龄16～78岁,中位年龄52岁;原发癌依次为食管癌31例、肺癌12例、喉咽部癌8例、肾透明细胞癌7例、直肠癌6例、黑色素瘤6例、乳腺癌3例、肌肉瘤3例、胃癌2例、肝癌、宫颈癌、非嗜铬性副神经节瘤、卵巢癌、唇鳞癌各1例.64例经过治疗(手术或放疗或化疗),原发癌转移至甲状腺时间间隔为1个月至26年,中位时间2.5年;79例以发现颈部肿物入院;80例行甲状腺转移癌切除术或放疗、化疗;83例中,生存期1个月至12年,中位生存期32个月.死亡原因为重要脏器的广泛癌转移.结论 甲状腺转移癌临床不常见,对既往有恶性肿瘤史近期发现甲状腺包块的患者应考虑转移癌可能,治疗以手术切除为主,辅以放疗、化疗可延长生存期.
目的 探討甲狀腺轉移癌的臨床髮病特點、診斷、治療及預後分析.方法 迴顧性分析83例甲狀腺轉移癌病例.結果 83例患者中,男性39例,女性39例,性彆不明5例;年齡16～78歲,中位年齡52歲;原髮癌依次為食管癌31例、肺癌12例、喉嚥部癌8例、腎透明細胞癌7例、直腸癌6例、黑色素瘤6例、乳腺癌3例、肌肉瘤3例、胃癌2例、肝癌、宮頸癌、非嗜鉻性副神經節瘤、卵巢癌、脣鱗癌各1例.64例經過治療(手術或放療或化療),原髮癌轉移至甲狀腺時間間隔為1箇月至26年,中位時間2.5年;79例以髮現頸部腫物入院;80例行甲狀腺轉移癌切除術或放療、化療;83例中,生存期1箇月至12年,中位生存期32箇月.死亡原因為重要髒器的廣汎癌轉移.結論 甲狀腺轉移癌臨床不常見,對既往有噁性腫瘤史近期髮現甲狀腺包塊的患者應攷慮轉移癌可能,治療以手術切除為主,輔以放療、化療可延長生存期.
목적 탐토갑상선전이암적림상발병특점、진단、치료급예후분석.방법 회고성분석83례갑상선전이암병례.결과 83례환자중,남성39례,녀성39례,성별불명5례;년령16～78세,중위년령52세;원발암의차위식관암31례、폐암12례、후인부암8례、신투명세포암7례、직장암6례、흑색소류6례、유선암3례、기육류3례、위암2례、간암、궁경암、비기락성부신경절류、란소암、진린암각1례.64례경과치료(수술혹방료혹화료),원발암전이지갑상선시간간격위1개월지26년,중위시간2.5년;79례이발현경부종물입원;80례행갑상선전이암절제술혹방료、화료;83례중,생존기1개월지12년,중위생존기32개월.사망원인위중요장기적엄범암전이.결론 갑상선전이암림상불상견,대기왕유악성종류사근기발현갑상선포괴적환자응고필전이암가능,치료이수술절제위주,보이방료、화료가연장생존기.
Objective To explore the clinical manifestations, diagnosis, treatment and prognosis of secondary thyroid neoplasms. Methods To retrospectively analyse clinical manifestations,examinations and treatment of 83 cases of secondary thyroid cancer, which were retrieved from CNKI (1994-2008). Results In all cases, 39 were male, 39 were female and 5 were unknow, aged from 16 to 78 years old, median age was 52. The primary cancers included 31 esophageal carcinomas, 12 lung cancers, 8 laryngopharynx cancers, 7 clear cell renal carcinomas, 6 rectal carcinomas, 6 melanomas, 3 breast cancers, 3 rhabdomyosarcoma, 2 gatric cancers, 1 liver cancer, 1 cervical cancer, 1 nonchromaffin paraganglioma,1 ovary cancer, 1 lip squamous cell carcinomac. 64 patients had undergone chemotherapy or surgery or radiotherapy. The intervals between finding of primary carcinoma and secondary thyroid carcinoma ranged from 1 month to 26 years with a median time of 2.5 years. Patients died of widespread metastases from 1 month to 12 years following the diagnosis of secondary carcinoma in thyroid, with a median time of 32 months. Conclusions Metastasis in the thyroid gland is uncommon and may cause a diagnostic problem. Metastatic cancer to the thyroid should be considered when a patient with histoy of malignant tumor has a recent found thyroid lesions. With the combination of Surgery, chemotherapy and radiotherapy, the survival of patients can be significantly prolonged.
