中华肝脏病杂志
中華肝髒病雜誌
중화간장병잡지
CHINESE JOURNAL OF HEPATOLOGY
2012年
9期
649-653
,共5页
肖静%陈萍%李小杉%庄勋%陆青云%高月霞
肖靜%陳萍%李小杉%莊勛%陸青雲%高月霞
초정%진평%리소삼%장훈%륙청운%고월하
肝炎,乙型,慢性%生活质量%影响因素
肝炎,乙型,慢性%生活質量%影響因素
간염,을형,만성%생활질량%영향인소
Hepatitis B,chronic%Quality of life%Influencing factors
目的 了解慢性乙型肝炎患者生活质量现状,并对其生活质量的影响因素进行分析. 方法 采用整群抽样方法,以世界卫生组织生活质量调查表(WHO QOL-BREF)及自制量表为调查工具,对268例慢性乙型肝炎患者(病例组)和205名正常人(对照组)进行病例对照研究.用独立样本成组t检验比较两组各项得分的差异,多元线性逐步回归法和单因素方差分析及多重比较分析其影响因素.结果 病例组生活质量总分、生理领域得分、心理领域得分、社会关系领域得分、环境领域得分、QOL自评得分和健康自评得分分别为(62.88±8.22)、(64.71±15.05)、(64.35±14.71)、(67.20±12.98)、(59.58±13.23)、(60.75±21.54)、(58.13±19.15)分,均低于对照组相应得分[(67.31±5.82)、(73.21±11.26)、(68.94±10.13)、(69.83±8.65)、(63.97±10.24)、(66.90±17.57)、(76.26±14.27)分],差异均有统计学意义(P值均＜0.05).多元线性逐步回归分析结果显示:抑郁、病情较重、自费、对收入有无明显影响、食欲较差、乏力和担心传染是影响生理领域得分的危险因素,治疗信心是保护因素(P值均＜ 0.05)；抑郁和复发是影响心理领域得分的危险因素,治疗信心和男性是保护因素(P值均＜ 0.05)；抑郁、对周围人的态度不满意、复发和高龄是影响社会关系领域得分的危险因素,社会支持和治疗信心是保护因素(P值均＜ 0.05),不同职业者之间社会关系领域得分差异有统计学意义(P＜ 0.01);抑郁、对周围人的态度不满意、居住在乡村和复发是影响环境领域得分的危险因素(P值均＜ 0.05).结论 在临床医疗护理过程中,重视有抑郁症状患者的早期治疗,加强患者心理健康护理,加强医患沟通,提高患者的社会支持水平,利于提高患者的生活质量.
目的 瞭解慢性乙型肝炎患者生活質量現狀,併對其生活質量的影響因素進行分析. 方法 採用整群抽樣方法,以世界衛生組織生活質量調查錶(WHO QOL-BREF)及自製量錶為調查工具,對268例慢性乙型肝炎患者(病例組)和205名正常人(對照組)進行病例對照研究.用獨立樣本成組t檢驗比較兩組各項得分的差異,多元線性逐步迴歸法和單因素方差分析及多重比較分析其影響因素.結果 病例組生活質量總分、生理領域得分、心理領域得分、社會關繫領域得分、環境領域得分、QOL自評得分和健康自評得分分彆為(62.88±8.22)、(64.71±15.05)、(64.35±14.71)、(67.20±12.98)、(59.58±13.23)、(60.75±21.54)、(58.13±19.15)分,均低于對照組相應得分[(67.31±5.82)、(73.21±11.26)、(68.94±10.13)、(69.83±8.65)、(63.97±10.24)、(66.90±17.57)、(76.26±14.27)分],差異均有統計學意義(P值均＜0.05).多元線性逐步迴歸分析結果顯示:抑鬱、病情較重、自費、對收入有無明顯影響、食欲較差、乏力和擔心傳染是影響生理領域得分的危險因素,治療信心是保護因素(P值均＜ 0.05)；抑鬱和複髮是影響心理領域得分的危險因素,治療信心和男性是保護因素(P值均＜ 0.05)；抑鬱、對週圍人的態度不滿意、複髮和高齡是影響社會關繫領域得分的危險因素,社會支持和治療信心是保護因素(P值均＜ 0.05),不同職業者之間社會關繫領域得分差異有統計學意義(P＜ 0.01);抑鬱、對週圍人的態度不滿意、居住在鄉村和複髮是影響環境領域得分的危險因素(P值均＜ 0.05).結論 在臨床醫療護理過程中,重視有抑鬱癥狀患者的早期治療,加彊患者心理健康護理,加彊醫患溝通,提高患者的社會支持水平,利于提高患者的生活質量.
목적 료해만성을형간염환자생활질량현상,병대기생활질량적영향인소진행분석. 방법 채용정군추양방법,이세계위생조직생활질량조사표(WHO QOL-BREF)급자제량표위조사공구,대268례만성을형간염환자(병례조)화205명정상인(대조조)진행병례대조연구.용독립양본성조t검험비교량조각항득분적차이,다원선성축보회귀법화단인소방차분석급다중비교분석기영향인소.결과 병례조생활질량총분、생리영역득분、심리영역득분、사회관계영역득분、배경영역득분、QOL자평득분화건강자평득분분별위(62.88±8.22)、(64.71±15.05)、(64.35±14.71)、(67.20±12.98)、(59.58±13.23)、(60.75±21.54)、(58.13±19.15)분,균저우대조조상응득분[(67.31±5.82)、(73.21±11.26)、(68.94±10.13)、(69.83±8.65)、(63.97±10.24)、(66.90±17.57)、(76.26±14.27)분],차이균유통계학의의(P치균＜0.05).다원선성축보회귀분석결과현시:억욱、병정교중、자비、대수입유무명현영향、식욕교차、핍력화담심전염시영향생리영역득분적위험인소,치료신심시보호인소(P치균＜ 0.05)；억욱화복발시영향심리영역득분적위험인소,치료신심화남성시보호인소(P치균＜ 0.05)；억욱、대주위인적태도불만의、복발화고령시영향사회관계영역득분적위험인소,사회지지화치료신심시보호인소(P치균＜ 0.05),불동직업자지간사회관계영역득분차이유통계학의의(P＜ 0.01);억욱、대주위인적태도불만의、거주재향촌화복발시영향배경영역득분적위험인소(P치균＜ 0.05).결론 재림상의료호리과정중,중시유억욱증상환자적조기치료,가강환자심리건강호리,가강의환구통,제고환자적사회지지수평,리우제고환자적생활질량.
Objective To survey patients with chronic hepatitis B (CHB) to determine their perceptions of CHB-related quality of life (QOF) and to determine the factors influencing this measure.Methods A total of 268 patients with CHB (disease group) and 205 healthy individuals (control group) completed the World Health Organization (WHO)QOL-BREF life assessment survey and a self-designed questionnaire of health and QOL.The groups' responses were comparatively analyzed by the cluster sampling method and the independent samples t-test.The strength of influence of each factor on the patients' perceptions of QOL was determined by multiple stepwise regression and one-way ANOVA.Results The disease group had significantly lower scores than the control group for overall QOL (62.88 ± 8.22 vs.67.31 ± 5.82),the physiological area (PHYS:64.71 ± 15.05 vs.73.21 ± 11.26),the psychological area (PSYCH:64.35 ± 14.71 vs.68.94 ± 10.13),the social relations area (SOCIL:67.20 ± 12.98 vs.69.83 ± 8.65),the environmental area (ENVIR:59.58±13.23 vs.63.97 ± 10.24),the QOL self-assessment (60.75 ± 21.54 vs.66.90 ± 17.57) and the health self-assessment (58.13 ± 19.15 vs.76.26 ± 14.27) (all,P ＜ 0.05).Multiple stepwise regression analysis identified the following parameters as risk factors of PHYS:depression (P＜ 0.001),perception of being seriously ill (P＜0.00 1),self-payment for treatment (P=0.003),CHB significant impact on income (P =0.002),poor appetite (P=0.002),languor (P＜0.001),and fear of infecting others (P=0.022).Confidence of treatment was a protective factor of PHYS (P=0.001).The risk factors of PSYCH were depression (P＜ 0.001) and recurrence (P＜0.001),and the protective factors were confidence of treatment (P =0.003) and male sex (P=0.014).The risk factors of SOCIL were depression (P＜0.001,dissatisfaction with the attitude of the people around (P=0.001),recurrence (P=0.008),and advanced age (P =0.009),and the protective factors were social support (P＜ 0.001) and confidence of treatment (P=0.015); however,the scores were significantly different for different occupations (P=0.008).The risk factors of ENVIR were depression (P＜0.001),dissatisfaction with the attitude of the people around (P ＜ 0.001),living in rural area (P=0.007),and recurrence (P=0.016).Conclusion Patients should be monitored for depressive symptoms during the course of clinical medical care for CHB so that psychological care may be initiated in a timely manner.It is important to strengthen communication between healthcare professionals and patients in order to improve the patient's perception of social support and quality of life.
