CAJ | 학술논문

目的探讨Rh母子血型不合新生儿溶血病检测新方法--单核单层检测.方法采集Rh抗体阴性对照组和阳性组共30例孕妇的血液标本,分别采用血清抗体鉴定和单核单层检测两种方法进行检测并比较.结果单核单层检测的灵敏度为77.8%,特异性为90.5%,阴性预示值为90.5%,阳性预示值为77.8%,准确率为86.7%.结论单核单层检测作为Rh系统新生儿溶血病诊断的辅助手段,有利于该病的早期诊断和及时治疗.
목적 탐토Rh모자혈형불합신생인용혈병검측신방법--단핵단층검측.방법 채집Rh항체음성대조조화양성조공30례잉부적혈액표본,분별채용혈청항체감정화단핵단층검측량충방법진행검측병비교.결과 단핵단층검측적령민도위77.8%,특이성위90.5%,음성예시치위90.5%,양성예시치위77.8%,준학솔위86.7%.결론 단핵단층검측작위Rh계통신생인용혈병진단적보조수단,유리우해병적조기진단화급시치료.
Objective To investigate the novel method monocyte monolayer assay for detecting Rh maternofetal blood group incompatible hemolytic disease of the newborn.Methods Blood samples were collected from 9 cases of Rh antibody negative pregnant women and 21 cases of Rh antibody positive ones. Serum antibody identification assay and monocyte monolayer assay were adopted, and the results were compared.Results The research showed that the sensitivity of monocyte monolayer assay was 77.8%, the specificity was 90.5%, the negative predicted value was 90.5%, the positive one was 77.8%, and the accuracy was 86.7%.Conclusion As a kind of assistant method for diagnosing Rh maternofetal blood group incompatible hemolytic disease of the newborn (HDN), monocyte monolayer assay is helpful for the early diagnosis and for Rh haemolytic disease of the newborn,it is beneficial for the early diagnosis and prompt therapy of HDN.