中华胰腺病杂志
中華胰腺病雜誌
중화이선병잡지
CHINESE JOURNAL OF PANCREATOLOGY
2010年
6期
392-394
,共3页
何军明%蔡仕霞%钟小生%仇成江%黄有星%王松%刘贤芬%谭志健%蔡炳勤
何軍明%蔡仕霞%鐘小生%仇成江%黃有星%王鬆%劉賢芬%譚誌健%蔡炳勤
하군명%채사하%종소생%구성강%황유성%왕송%류현분%담지건%채병근
胰腺炎,急性坏死性%甘遂%压力%结胸证
胰腺炎,急性壞死性%甘遂%壓力%結胸證
이선염,급성배사성%감수%압력%결흉증
Pancreatitis,acute necrotizing%Euphorbia kansui%Pressure%Jiexiong syndrome
目的 观察中药甘遂辅助治疗重症急性胰腺炎(SAP)并发腹腔间隔室综合征(ACS)的疗效.方法 收集SAP并发ACS患者16例,按随机数字表法分为甘遂组和对照组.对照组按常规行禁食、抗休克、抗感染、营养支持等治疗,甘遂组在对照组治疗方案基础上加用甘遂.对比两组临床和实验室指标、结果甘遂组腹痛缓解时间、肠呜音恢复时间、血淀粉酶恢复正常时间及体温、白细胞计数恢复正常时间分别为(7.6±2.3)d、(6.1±3.1)d、(5.9±3.3)d、(5.2±3.2)d、(6.3±2.1)d,较对照组的(1 1.7±2.1)d、(11.2±2.3)d、(10.2±2.7)d、(9.2±3.5)d、(11.1±3.3)d有显著差异(P＜0.01);治疗后第3、4、5天两组病例腹内压差异显著[(19.8±3.1)cmH2O对(23.7±2.9)cmH2O、(12.3±2.7)cmH2O对(21.3±1.5)cmH2O、(8.2±3.1)cmH2O对(17.3±2.3)cmH2O,P值均＜0.05].结论 胰腺炎与中医结胸证有密切相关性,甘遂能够有效降低SAP所致的腹内高压.
目的 觀察中藥甘遂輔助治療重癥急性胰腺炎(SAP)併髮腹腔間隔室綜閤徵(ACS)的療效.方法 收集SAP併髮ACS患者16例,按隨機數字錶法分為甘遂組和對照組.對照組按常規行禁食、抗休剋、抗感染、營養支持等治療,甘遂組在對照組治療方案基礎上加用甘遂.對比兩組臨床和實驗室指標、結果甘遂組腹痛緩解時間、腸嗚音恢複時間、血澱粉酶恢複正常時間及體溫、白細胞計數恢複正常時間分彆為(7.6±2.3)d、(6.1±3.1)d、(5.9±3.3)d、(5.2±3.2)d、(6.3±2.1)d,較對照組的(1 1.7±2.1)d、(11.2±2.3)d、(10.2±2.7)d、(9.2±3.5)d、(11.1±3.3)d有顯著差異(P＜0.01);治療後第3、4、5天兩組病例腹內壓差異顯著[(19.8±3.1)cmH2O對(23.7±2.9)cmH2O、(12.3±2.7)cmH2O對(21.3±1.5)cmH2O、(8.2±3.1)cmH2O對(17.3±2.3)cmH2O,P值均＜0.05].結論 胰腺炎與中醫結胸證有密切相關性,甘遂能夠有效降低SAP所緻的腹內高壓.
목적 관찰중약감수보조치료중증급성이선염(SAP)병발복강간격실종합정(ACS)적료효.방법 수집SAP병발ACS환자16례,안수궤수자표법분위감수조화대조조.대조조안상규행금식、항휴극、항감염、영양지지등치료,감수조재대조조치료방안기출상가용감수.대비량조림상화실험실지표、결과감수조복통완해시간、장오음회복시간、혈정분매회복정상시간급체온、백세포계수회복정상시간분별위(7.6±2.3)d、(6.1±3.1)d、(5.9±3.3)d、(5.2±3.2)d、(6.3±2.1)d,교대조조적(1 1.7±2.1)d、(11.2±2.3)d、(10.2±2.7)d、(9.2±3.5)d、(11.1±3.3)d유현저차이(P＜0.01);치료후제3、4、5천량조병례복내압차이현저[(19.8±3.1)cmH2O대(23.7±2.9)cmH2O、(12.3±2.7)cmH2O대(21.3±1.5)cmH2O、(8.2±3.1)cmH2O대(17.3±2.3)cmH2O,P치균＜0.05].결론 이선염여중의결흉증유밀절상관성,감수능구유효강저SAP소치적복내고압.
Objective To investigate the treatment effects of Kansui root on severe acute pancreatitis (SAP) with abdominal compartment syndrome (ACS).Methods 16 cases of SAP were randomly divided into kansui root treatment group and control group according to random number table.Patients in control group received routine treatment including fasting, anti-shock, antibiotics and nutritional support.And the patients in kansui root group received routine treatment plus kansui root therapy.The clinical and laboratory parameters were determined and compared between the two groups.Results The relieving time of abdominal pain, bowel sound, the recovery time of hyperamylasemia, body temperature and leukocyte count in treatment group was (7.6±2.3)d, (6.1 ±3.1)d, (5.9±3.3)d, (5.2 ±3.2) d, (6.3 ±2.1)d, which were significantly shorter than those in control group [ ( 11.7 ± 2.1 ) d, ( 11.2 ± 2.3d, ( 10.2 ± 2.7) d, (9.2 ± 3.5 ) d, ( 11.1 ±3.3)d, P＜0.01 ) ].At the 3rd, 4th and 5th day, the intra-abdominal pressure in treatment group were also significantly lower than those in control group[ ( 19.8 ±3.1 )cmH2O vs(23.7 ±2.9) cmH2O, ( 12.3 ±2.7) cmH2O vs (21.3±1.5)cmH2O,(8.2±3.1)cmH2O vs (17.3 ±2.3)cmH2O,P＜0.05].Conclusions Severe acute pancreatitis has close relationship with Jiexiong syndrome in traditional chinese medicine.Kansui root is an effective therapy for alleviating high intra-abdominal pressure.
