CAJ | 학술논문

目的观察阿奇霉素治疗婴幼儿急性细菌性肺炎的有效性与安全性.方法采用开放随机对照试验方法,以红霉素作为对照药物,比较研究阿奇霉素治疗婴幼儿急性细菌性肺炎的临床疗效和安全性.结果阿奇霉素组的痊愈率和总有效率分别为75.5%和90.6%,不良反应发生率为9.3%;而红霉素组的痊愈率和总有效率分别为36.0%和68.0%,不良反应发生率为30.4%.两组比较,差异均有统计学意义(均P<0.05).结论阿奇霉素治疗婴幼儿急性细菌性肺炎,方便、安全、有效.
목적 관찰아기매소치료영유인급성세균성폐염적유효성여안전성.방법 채용개방수궤대조시험방법,이홍매소작위대조약물,비교연구아기매소치료영유인급성세균성폐염적림상료효화안전성.결과 아기매소조적전유솔화총유효솔분별위75.5%화90.6%,불량반응발생솔위9.3%;이홍매소조적전유솔화총유효솔분별위36.0%화68.0%,불량반응발생솔위30.4%.량조비교,차이균유통계학의의(균P<0.05).결론 아기매소치료영유인급성세균성폐염,방편、안전、유효.
Objective To evaluate the clinical efficacy and safety of injection azithromycin in the treatment of the acute bacteria pneumonia of infant. Methods A randomized controlled open trial was carried out. Erythromycin as a controll drug was compared the clinical efficacy and safety with azithromycin as a test drug. Results In azithro-mycin group,the clinical effective rate was 90.6% ;the fully recovered rate was 75.5%. While those of erythromycin group were 68.0% ,36.0% respectively. The incidence of adverse reaction was 9.3% and 30.4% respectively in two groups. Conclusion Injection azithromycin of new macrofides type is a kind of effective and safe anti-bacterial drug.