国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2011年
22期
1741-1745
,共5页
间质性肺疾病%特发性肺纤维化%肺肿瘤%肿瘤标记物
間質性肺疾病%特髮性肺纖維化%肺腫瘤%腫瘤標記物
간질성폐질병%특발성폐섬유화%폐종류%종류표기물
Interstitial lung disease%Idiopathic pulmonary fibrosis%Lung neoplasm%Tumor marker
间质性肺疾病(ILD)患者中肺癌的发病率增高,特别是特发性肺纤维化合并肺癌的报道最多.ILD合并肺癌的病理类型以鳞状细胞癌最多,好发于肺下叶和外周部位.ILD的一些肿瘤标记物增高,与疾病的活动程度、严重程度、肺纤维化程度和病情预后等有关,并且具有一定的诊断价值.ILD的肿瘤标记物增高可能是其合并肺癌的危险因素.本文对ILD合并肺癌的流行病学研究和ILD的肿瘤标记物的研究进展做一综述.
間質性肺疾病(ILD)患者中肺癌的髮病率增高,特彆是特髮性肺纖維化閤併肺癌的報道最多.ILD閤併肺癌的病理類型以鱗狀細胞癌最多,好髮于肺下葉和外週部位.ILD的一些腫瘤標記物增高,與疾病的活動程度、嚴重程度、肺纖維化程度和病情預後等有關,併且具有一定的診斷價值.ILD的腫瘤標記物增高可能是其閤併肺癌的危險因素.本文對ILD閤併肺癌的流行病學研究和ILD的腫瘤標記物的研究進展做一綜述.
간질성폐질병(ILD)환자중폐암적발병솔증고,특별시특발성폐섬유화합병폐암적보도최다.ILD합병폐암적병리류형이린상세포암최다,호발우폐하협화외주부위.ILD적일사종류표기물증고,여질병적활동정도、엄중정도、폐섬유화정도화병정예후등유관,병차구유일정적진단개치.ILD적종류표기물증고가능시기합병폐암적위험인소.본문대ILD합병폐암적류행병학연구화ILD적종류표기물적연구진전주일종술.
A number of studies have shown a high incidence of lung cancer in patients with interstitial lung disease (ILD),especially idiopathic pulmonary fibrosis.The most pathological type of ILD combined with lung cancer is squamous cell carcinoma,and it usually occurs in the lower lobes and peripheral parts.The increase of some tumor markers of ILD is associated with the degree of disease activity,severity,fibrosis,prognosis and so on,and it has a certain diagnostic value.The increase of ILD tumor markers may be the risk factors of ILD combined with lung cancer.This paper makes a review on the epidemiological study of ILD combined with lung cancer and the research progress of ILD tumor markers.
