CAJ | 학술논문

目的探讨气道侵袭性曲霉病临床表现、诊断及治疗方法.方法结合我院收治的1例气道侵袭性曲霉病病例的临床资料及国内外文献报道进行综合分析.结果患者女性,49岁,间断咳嗽、咯痰、发热1个月,胸部CT提示左下叶实变,在外院抗炎、抗结核治疗1个月,未见明显好转收入院.入院后行气管镜检查,活检提示曲霉菌感染,抗真菌及气管镜下反复高频电凝治疗后,患者症状明显好转.结论气道侵袭性曲霉病较少见,曲霉在气道管腔内呈团块状生长,导致支气管阻塞、扩张,病情进展快,侵袭性强,早期、足疗程抗真菌治疗同时气管镜介入局部高频电凝治疗,可取得满意的疗效.
목적 탐토기도침습성곡매병림상표현、진단급치료방법.방법 결합아원수치적1례기도침습성곡매병병례적림상자료급국내외문헌보도진행종합분석.결과 환자녀성,49세,간단해수、각담、발열1개월,흉부CT제시좌하협실변,재외원항염、항결핵치료1개월,미견명현호전수입원.입원후행기관경검사,활검제시곡매균감염,항진균급기관경하반복고빈전응치료후,환자증상명현호전.결론기도침습성곡매병교소견,곡매재기도관강내정단괴상생장,도치지기관조새、확장,병정진전쾌,침습성강,조기、족료정항진균치료동시기관경개입국부고빈전응치료,가취득만의적료효.
Objective To investigate the clinical manifestations,diagnosis and treatment of airway invasive aspergillosis.Methods The clinical data of one case of airway invasive aspergillosis in our hospital was reported and the related literatures were reviewed and analyzed.Results A 49-year-old female patient complained of intermittent cough,sputum and fever for one month.Chest computer tomography showed consolidation tips of left lung lower lobe.After anti-inflammatory,anti-tuberculosis treatment for one month in other hospital,the patient had no significant improvement in symptoms.In our hospital,the patient received bronchoscopic examination and the result was aspergillus infection in biopsy tips.After anti-fungal therapy and repeated tracheal endoscopic high-frequency coagulation therapy,the patient's symptoms improved.Conclusions Airway invasive aspergillosis is uncommon.Aspergillus in the airway lumen grows as lumps,it causes bronchial obstruction and expansion,accompanies rapid progression and strong invasion.Early adequate anti-fungal therapy and bronchoscopy involvement of local high-frequency coagulation therapy can lead to satisfactory results.