CAJ | 학술논문

目的：研究99mTc-甲氧基异丁基异腈（99mTc- MIBI）显像鉴别诊断乳腺肿物的良、恶性及探测腋淋巴结转移的情况。方法：对51例可触及的乳腺肿物及11例乳腺癌术后疑腋淋巴结转移患者分别于注射99mTc-MIBI后10和60 min行平面显像，半定量分析肿物部位的摄取比值（uptake ratio，UR），均与病理结果对比。结果：99mTc-MIBI平面显像对可触及的乳腺肿物诊断乳腺癌的敏感性为93.3%，特异性为95.2%；阳性预测值为96.6%，阴性预测值为90.9%。探测腋淋巴结转移的敏感性为64.0%，特异性为94.1%；阳性预测值为94.1%，阴性预测值为64.0%。结论：99mTc-MIBI平面显像鉴别乳腺肿物的良、恶性及探测腋淋巴结转移有较高的敏感性和特异性。
목적：연구99mTc-갑양기이정기이정（99mTc- MIBI）현상감별진단유선종물적량、악성급탐측액림파결전이적정황。방법：대51례가촉급적유선종물급11례유선암술후의액림파결전이환자분별우주사99mTc-MIBI후10화60 min행평면현상，반정량분석종물부위적섭취비치（uptake ratio，UR），균여병리결과대비。결과：99mTc-MIBI평면현상대가촉급적유선종물진단유선암적민감성위93.3%，특이성위95.2%；양성예측치위96.6%，음성예측치위90.9%。탐측액림파결전이적민감성위64.0%，특이성위94.1%；양성예측치위94.1%，음성예측치위64.0%。결론：99mTc-MIBI평면현상감별유선종물적량、악성급탐측액림파결전이유교고적민감성화특이성。
Objective: To identify benign and malignant breast lesions and detect metastatic axillary lymph nodes using99mTc-methoxyisobutyl isonitrile(MIBI) imaging. Methods: Fifty-one women with a palpable breast lesions and 11 patients suspicious of metastatic lymph node after primary breast cancer operation were studied with planar imaging 10 min and 60 min after injection of 99mTc-MIBI. Semiquantitative analysis of uptake ratio(UR) of 99mTc-MIBI in locations of tumour and lymph nodes were performed. All the results were compared with pathologic study. Results: In palpable lesions, the sensitivity of 99mTc-MIBI planar imaging for detecting primary breast cancer was 93.3% and the specificity was 95.2%;The positive predictive value was 96.6%. The negative predictive value was 90.9%. The sensitivity of 99mTc-MIBI planar imaging to detect metastatic axillary lymph nodes was 64.0% and the specificity was 94.1%;The positive predictive value was 94.1%. The negative predictive value was 64.0%. Conclusion: 99mTc-MIBI planar imaging has high sensitivity and specificity for differentiation of breast tumors and detection of axillary lymph node involvement.