CAJ | 학술논문

目的通过动态检测产后大出血输血治疗中的D-二聚体水平,以评估疗效及新鲜血栓形成的可能性.方法回顾性分析2008年本院10例产后大出血抢救中的D-二聚体水平和凝血四项结果,同时检测20例正常分娩产妇的D-二聚体水平作对照分析,并采用t检验进行统计分析.结果产后大出血抢救中的血浆D-二聚体水平显著高于正常对照组,差异有显著性(P<0.01).动态监测10例抢救患者的血浆D-二聚体水平随有效治疗病情好转后而逐渐降低.结论 D-二聚体是继发性纤溶标志,其检测结果能反映患者的血管内皮损伤及凝血、抗凝血和纤溶功能,对了解机体的血液凝固状态,预测是否有微血栓的形成和出血倾向,预测弥散性血管内凝血(DIC)发生、发展及患者的预后具有重要的临床价值.
목적 통과동태검측산후대출혈수혈치료중적D-이취체수평,이평고료효급신선혈전형성적가능성.방법 회고성분석2008년본원10례산후대출혈창구중적D-이취체수평화응혈사항결과,동시검측20례정상분면산부적D-이취체수평작대조분석,병채용t검험진행통계분석.결과 산후대출혈창구중적혈장D-이취체수평현저고우정상대조조,차이유현저성(P<0.01).동태감측10례창구환자적혈장D-이취체수평수유효치료병정호전후이축점강저.결론 D-이취체시계발성섬용표지,기검측결과능반영환자적혈관내피손상급응혈、항응혈화섬용공능,대료해궤체적혈액응고상태,예측시부유미혈전적형성화출혈경향,예측미산성혈관내응혈(DIC)발생、발전급환자적예후구유중요적림상개치.
Objective To dynamic monitor the level of D--dimer after transfusion treatment of postpartum hemorrhage and the possibility of thrombosis. Methods To retrospective analyze and compare of the level of D-dimer of 10 cases with postpartum hemorrhage, while the one in 20 eases of normal confinement in our hospital of year 2008. Results The level of D-dimer in the ease of postpartum hemorrhage was significantly higher than the one in the ease of normal confinement, and this difference indicated important significance(P<0.01).Dynamic monitoring 10 eases of emergency treatment of patients with plasma D-dimer levels with the effective condition improved after treatment and gradually decreased. Conclusion D-dimer is the main mark of secondary fibrinolysis, and the results reflect the function of D-dimer in vascular endothelial injury and blood coagulation, anti-coagulation and fibrinolytie. Furthermore, it has important significance in the understanding of the body's blood coagulation status and the prediction of mierothrombus formation, bleeding tendency, or the occurrence and development of disseminated intravaseular coagulation(DIC), development