中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2010年
6期
445-447
,共3页
高莹莹%胥亚男%庄铭忠%曾奕明%苏清炎%陈晓阳
高瑩瑩%胥亞男%莊銘忠%曾奕明%囌清炎%陳曉暘
고형형%서아남%장명충%증혁명%소청염%진효양
眼睑疾病,松弛%睡眠呼吸暂停,阻塞性%体重指数%血氧饱和度
眼瞼疾病,鬆弛%睡眠呼吸暫停,阻塞性%體重指數%血氧飽和度
안검질병,송이%수면호흡잠정,조새성%체중지수%혈양포화도
Eyelid disease,floppy%Sleep apnea,obstructive%Body mass index%SaO2
目的 通过分析眼睑松弛和阻塞性睡眠呼吸暂停综合征(OSAHS)各指标的关系,初步探讨眼睑松弛发生的病理生理基础.方法 福建医科大学附属第二医院呼吸科睡眠监测室于2006年10月至2007年3月期间行多导睡眠监测(PSG)并确诊为OSAHS的患者44例,行眼睑松弛度检查,记录年龄、性别、体重指数(BMI)、睡眠呼吸暂停低通气指数(AHI)、快速动眼期(REM)占睡眠时间的百分数、血氧饱和度(SaO2)＜90%的时间等参数.随机选择在我院体检中心做体检,无睡眠打鼾及睡眠质量问题,且既往无眼病史的正常人100名作为对照.OSAHS与正常对照组眼睑松弛发生率的比较采用卡方检验;OSAHS患者中眼睑松弛者与无眼睑松弛者相关指数的比较采用两独立样本t检验,眼睑松弛与A HI及BMI的相关性采用直线回归分析.结果 44例OSAHS患者中,眼睑松弛者27例(61%),高于正常对照组(7%)(x2=5.007,P＜0.01).OSAHS患者中,眼睑松弛者的AHI为(54.5±21.0)次/h,明显高于无眼睑松弛者(31.1±21.9)次/h(t=3.229,P=0.036);眼睑松弛者的BMI为(29.7±4.8)kg/m2,明显高于无眼睑松弛者(25.3±3.5)kg/m2(t=3.556,P=0.006).眼睑松弛与AHI及BMI成正相关(r=0.494、0.447,P＜0.05),而与REM及SaO2＜90%的时间等参数的相关性无统计学意义.结论 眼睑松弛多见于OSAHS患者,高的BMI和AHI是眼睑松弛的危险因素,提示肥胖和低通气可能是眼睑松弛产生和发展的原因.
目的 通過分析眼瞼鬆弛和阻塞性睡眠呼吸暫停綜閤徵(OSAHS)各指標的關繫,初步探討眼瞼鬆弛髮生的病理生理基礎.方法 福建醫科大學附屬第二醫院呼吸科睡眠鑑測室于2006年10月至2007年3月期間行多導睡眠鑑測(PSG)併確診為OSAHS的患者44例,行眼瞼鬆弛度檢查,記錄年齡、性彆、體重指數(BMI)、睡眠呼吸暫停低通氣指數(AHI)、快速動眼期(REM)佔睡眠時間的百分數、血氧飽和度(SaO2)＜90%的時間等參數.隨機選擇在我院體檢中心做體檢,無睡眠打鼾及睡眠質量問題,且既往無眼病史的正常人100名作為對照.OSAHS與正常對照組眼瞼鬆弛髮生率的比較採用卡方檢驗;OSAHS患者中眼瞼鬆弛者與無眼瞼鬆弛者相關指數的比較採用兩獨立樣本t檢驗,眼瞼鬆弛與A HI及BMI的相關性採用直線迴歸分析.結果 44例OSAHS患者中,眼瞼鬆弛者27例(61%),高于正常對照組(7%)(x2=5.007,P＜0.01).OSAHS患者中,眼瞼鬆弛者的AHI為(54.5±21.0)次/h,明顯高于無眼瞼鬆弛者(31.1±21.9)次/h(t=3.229,P=0.036);眼瞼鬆弛者的BMI為(29.7±4.8)kg/m2,明顯高于無眼瞼鬆弛者(25.3±3.5)kg/m2(t=3.556,P=0.006).眼瞼鬆弛與AHI及BMI成正相關(r=0.494、0.447,P＜0.05),而與REM及SaO2＜90%的時間等參數的相關性無統計學意義.結論 眼瞼鬆弛多見于OSAHS患者,高的BMI和AHI是眼瞼鬆弛的危險因素,提示肥胖和低通氣可能是眼瞼鬆弛產生和髮展的原因.
목적 통과분석안검송이화조새성수면호흡잠정종합정(OSAHS)각지표적관계,초보탐토안검송이발생적병리생리기출.방법 복건의과대학부속제이의원호흡과수면감측실우2006년10월지2007년3월기간행다도수면감측(PSG)병학진위OSAHS적환자44례,행안검송이도검사,기록년령、성별、체중지수(BMI)、수면호흡잠정저통기지수(AHI)、쾌속동안기(REM)점수면시간적백분수、혈양포화도(SaO2)＜90%적시간등삼수.수궤선택재아원체검중심주체검,무수면타한급수면질량문제,차기왕무안병사적정상인100명작위대조.OSAHS여정상대조조안검송이발생솔적비교채용잡방검험;OSAHS환자중안검송이자여무안검송이자상관지수적비교채용량독립양본t검험,안검송이여A HI급BMI적상관성채용직선회귀분석.결과 44례OSAHS환자중,안검송이자27례(61%),고우정상대조조(7%)(x2=5.007,P＜0.01).OSAHS환자중,안검송이자적AHI위(54.5±21.0)차/h,명현고우무안검송이자(31.1±21.9)차/h(t=3.229,P=0.036);안검송이자적BMI위(29.7±4.8)kg/m2,명현고우무안검송이자(25.3±3.5)kg/m2(t=3.556,P=0.006).안검송이여AHI급BMI성정상관(r=0.494、0.447,P＜0.05),이여REM급SaO2＜90%적시간등삼수적상관성무통계학의의.결론 안검송이다견우OSAHS환자,고적BMI화AHI시안검송이적위험인소,제시비반화저통기가능시안검송이산생화발전적원인.
Objective To analyze the parameters of floppy eyelid and obstructive sleep apnea-hypopnea syndrome (OSAHS) in order to discover the pathological basis of eyelid hyperlaxity.Methods Forty-four patients referred to the respiratory department of The Second Affiliated Hospital of Fujian Medical University and diagnosed with OSAHS were included in this study. Eyelid laxity and polysomnography parameters such as age, sex, body mass index (BMI), apnea and hypopnea index (AHI), percentage of REM during sleep, and time of SaO2＜90%, were recorded and analyzed.The control group consisted of 100 healthy people who underwent a routine physical checkup and did not have sleep disorder. Results In 44 patients who were found to have OSAHS, 27 patients (61%)were found to have floppy eyelid, which was higher than the control group (7%)(x2=5.007, P＜0.01).AHI in patients with floppy eyelid was (54.5±21.0)/h, which was higher than (31.1±21.9)/h in those without floppy eyelid (t=3.229, P=0.036). BMI in the floppy eyelid group was (29.7±4.8)kg/m2, which was higher than (25.3±3.5)kg/m2 in the non-floppy eyelid group (t=3.556, P=0.006). There was no difference in the percent of REM and time of SaO2＜90% in patients with or without floppy eyelid.AHI and BMI were correlated with floppy eyelid (r=0.494, 0.447, P＜0.05), but REM and SaO2＜90%were not correlated with floppy eyelid. Conclusion Floppy eyelid is common in OSAHS patients. High BMI and AHI are risk factors for floppy eyelid. The cause and development of eyelid hyperlaxity might be due to obesity and hypopnea.
