CAJ | 학술논문

目的探讨EB病毒急性感染与胎儿水肿的关系,了解妊娠中晚期EB病毒感染对母儿的危害及妊娠结局的影响.方法对孕期B超检查符合胎儿水肿综合征的40例孕妇作为研究组,进行孕妇血清EBEA-IgM检测,观察妊娠结局,并随机抽取同期101例胎儿正常的孕妇血作为对照组.结果研究组孕妇EBEA-IgM阳性率(95%)显著高于对照组(48.5%,P＜0.01),且死胎、活产、胎儿异常引产的比例与对照组相比差异有统计学意义(P＜0.01),活产中早产(40%)率明显高于对照组(10.9%,P＜0.05).结论孕期急性EB病毒感染与胎儿水肿的发生存在相关性,应重视孕期EB病毒感染的检测.
목적 탐토EB병독급성감염여태인수종적관계,료해임신중만기EB병독감염대모인적위해급임신결국적영향.방법 대잉기B초검사부합태인수종종합정적40례잉부작위연구조,진행잉부혈청EBEA-IgM검측,관찰임신결국,병수궤추취동기101례태인정상적잉부혈작위대조조.결과 연구조잉부EBEA-IgM양성솔(95%)현저고우대조조(48.5%,P＜0.01),차사태、활산、태인이상인산적비례여대조조상비차이유통계학의의(P＜0.01),활산중조산(40%)솔명현고우대조조(10.9%,P＜0.05).결론 잉기급성EB병독감염여태인수종적발생존재상관성,응중시잉기EB병독감염적검측.
Objective To explore the relationship of acute infections of Epstein-Barr virus and hydrops fetalis and explore the harm to fetuses and the affection on pregnancy outcomes caused by acute EBV infection during pregnancy. Methods 40 cases hydrops fetalis were diagnosed by ultrasonography. The difference between the EBEA-IgM positive and negative patients blood were studied. 101 cases over the same period of pregnant women with normal fetuses were enrolled as a control group. Results The positive rate of EBEA-IgM in pregnant women (95%) was significantly higher than that of control group(48.5%,P＜0.01). And the differences of the ratio of still birth and live birth and abnormal fetuses induction of labor between the groups were statistically significant（P＜0.01）. Premature birth among the live birth (40%) was obviously higher than that of control group (10.9%,P＜0.05). Conclusions Active infection of EBV in pregnancy was relevant to the hydrops fetalis and there need to pay attention to the detection of EBV during pregnancy.