CAJ | 학술논문

目的探讨对拟诊为肺炎支原体肺炎患儿动态检测血清抗肺炎支原体抗体IgM(MP-IgM)的临床意义,分析不同时间段MP-IgM阳性患儿的临床特点.方法取患儿静脉血,应用MP-IgM试剂盒对218例拟诊为肺炎支原体肺炎患儿进行MP-IgM检测.结果 218例拟诊为肺炎支原体肺炎患儿中MP-IgM阳性172例(78.8%),病后第2周阳性89例,第3周阳性52例,第4周阳性3l例.MP-IgM阳性出现较晚的患儿有以下特点:①发热时间长,年龄偏小.②肺部体征出现晚,肺部啰音、X线表现消散迟.③常有皮疹、肝脏损害等肺外表现.④联合应用抗生素比例高.⑤对抗生素疗程的依从性好.结论对拟诊为肺炎支原体肺炎患儿动态检测血清中MP-IgM,能够提高肺炎支原体肺炎的确诊率,指导正确选择抗生素,减少不合理用药.
목적 탐토대의진위폐염지원체폐염환인동태검측혈청항폐염지원체항체IgM(MP-IgM)적림상의의,분석불동시간단MP-IgM양성환인적림상특점.방법 취환인정맥혈,응용MP-IgM시제합대218례의진위폐염지원체폐염환인진행MP-IgM검측.결과 218례의진위폐염지원체폐염환인중MP-IgM양성172례(78.8%),병후제2주양성89례,제3주양성52례,제4주양성3l례.MP-IgM양성출현교만적환인유이하특점:①발열시간장,년령편소.②폐부체정출현만,폐부라음、X선표현소산지.③상유피진、간장손해등폐외표현.④연합응용항생소비례고.⑤대항생소료정적의종성호.결론 대의진위폐염지원체폐염환인동태검측혈청중MP-IgM,능구제고폐염지원체폐염적학진솔,지도정학선택항생소,감소불합리용약.
Objective To evaluate the clinical significance of ambulatory detection of anti -mycoplasma pneumoniae IgM ( MP - IgM ) in children preliminarily diagnosed as mycoplasma pneumoniae pneumonia and analyze the clinical features of them. Methods The MP - IgM were detected in 218 children preliminarily diagnosed as mycoplasma pneumoniae pneumonia using MP antibody reagents. Results In the 218 children, 172 cases showed positive MP antibody and the positivity rate was 78.8%.Positive cases was 89 patients during the second week of the onset of illness, 52 cases in the third week and 31 cases in the fourth week. The cases whose MP - IgM were positive in the fourth week of the illness were younger, had longer days of fever and more complications of other organ. They also had higher rate of combined usage of antibiotics. Their compliance with the course of treatment were better. Conclusions The ambulatory detection of MP - IgM was useful for choosing of antibiotics in children preliminarily diagnosed as mycoplasma pneumoniae pneumonia.