CAJ | 학술논문

近年随着肿瘤治疗不断发展,针对基因治疗的药物在肿瘤的降期和局部控制中发挥着重大的作用.结直肠癌内部基因的异质性促进了肿瘤的发生发展,关系着靶向药物选择及疗效,其必然成为肿瘤个体化治疗瓶颈的重要突破点.
근년수착종류치료불단발전,침대기인치료적약물재종류적강기화국부공제중발휘착중대적작용.결직장암내부기인적이질성촉진료종류적발생발전,관계착파향약물선택급료효,기필연성위종류개체화치료병경적중요돌파점.
Cancer treatment has been continuously improved in recent year. Genetically targeted therapy has played a significant role in tumor reduction and local control. Genetic heterogeneity of colorectal cancer affects not only tumor development and progression, but also the selection and efficiency of targeted drugs, thus may become a breakthrough towards tackling the bottleneck in personalized medicine.