CAJ | 학술논문

目的探讨硫酸镁联合复方聚乙二醇电解质散在胶囊内镜检查术前肠道准备中的应用价值.方法 81例患者分成单纯口服复方聚乙二醇电解质散组(A组,n =41)和硫酸镁联合复方聚乙二醇电解质散口服组(B组,n =40),比较两组病变检出情况、肠道准备评分结果、胶囊滞留发生情况及电解质、肝肾功能检测结果.结果 A组病变检出率为65.9％( 27/41),B组为62.5％(25/40),差异无统计学意义(x2=0.099,P＞0.05)；A组肠道准备评分≤4分19例、≥6分22例,B组≤4分28例、≥6分12例,差异有统计学意义(x2=4.653,P＜0.05)；A组胶囊滞留发生率为2.4％(1/41),B组为5.0％ (2/40),差异无统计学意义(x2=0.372,P＞0.05).两组患者服用肠道准备药物过程中均无明显腹痛、恶心、呕吐、心慌等不适,服药后两组电解质水平及肝肾功能指标值比较差异均无统计学意义(P＞0.05).结论硫酸镁联合复方聚乙二醇电解质散应用于胶囊内镜检查术前肠道准备具有较好的应用价值.
목적 탐토류산미연합복방취을이순전해질산재효낭내경검사술전장도준비중적응용개치.방법 81례환자분성단순구복복방취을이순전해질산조(A조,n =41)화류산미연합복방취을이순전해질산구복조(B조,n =40),비교량조병변검출정황、장도준비평분결과、효낭체류발생정황급전해질、간신공능검측결과.결과 A조병변검출솔위65.9％( 27/41),B조위62.5％(25/40),차이무통계학의의(x2=0.099,P＞0.05)；A조장도준비평분≤4분19례、≥6분22례,B조≤4분28례、≥6분12례,차이유통계학의의(x2=4.653,P＜0.05)；A조효낭체류발생솔위2.4％(1/41),B조위5.0％ (2/40),차이무통계학의의(x2=0.372,P＞0.05).량조환자복용장도준비약물과정중균무명현복통、악심、구토、심황등불괄,복약후량조전해질수평급간신공능지표치비교차이균무통계학의의(P＞0.05).결론 류산미연합복방취을이순전해질산응용우효낭내경검사술전장도준비구유교호적응용개치.
Objective To evaluate magnesium sulfate and compound polyethylene glycol electrolyte in bowel preparation before capsule endoscopy.Methods A total of 81 patients were randomly divided into two groups.Group A (n =41 ) received compound polyethylene glycol electrolyte,and group B (n =40) received magnesium sulfate combined with compound polyethylene glycol electrolyte. Positive detection rate,intestinal preparation score,the incidence of capsule retention and solution quality,liver and kidney function were compared between those two groups.Results The positive detection rates of capsule endoscopy were 65.9％ (27/41) in group A and 62.5％ (25/40) in group B,which were nonsignificantly different (x2 =0.099,P ＞ 0.05).The intestinal preparation scores of 19 patients in group A were ≤4 and those of 22 patients were ≥6,while those of 28 patients in group B were ≤4 and of 12 patients were ≥6,which were significantly different (x2 =4.653,P ＜ 0.05). The rates of capsule retention of group A and B were 2.4％( 1/41 ) and 5.0％ (2/40) respectively,which were not significantly different (x2 =0.372,P ＞ 0.05 ).Obvious abdominal pain,nausea or vomitting occurred in no patients of the two groups.There was no difference in electrolyte level or liver and kidney function between those two groups (P ＞ 0.05 ).Conclusion Magnesium sulfate combined with compound polyethylene glycol electrolyte is applicable for the bowel preparation before capsule endoscopy.