中华医学美学美容杂志
中華醫學美學美容雜誌
중화의학미학미용잡지
CHINESE JOURNAL OF MEDICAL AESTHETICS AND COSMETOLOGY
2010年
5期
323-325
,共3页
胡金贵%陈雪红%柳江燕%王正江%鲁秀娟
鬍金貴%陳雪紅%柳江燕%王正江%魯秀娟
호금귀%진설홍%류강연%왕정강%로수연
32磷%平阳霉素%婴幼儿%血管瘤
32燐%平暘黴素%嬰幼兒%血管瘤
32린%평양매소%영유인%혈관류
32P%Pinyangmycin%Infants and children%Hemangioma
目的 探讨和评价小剂量32P和平阳霉素联合治疗婴幼儿颌面部血管瘤的疗效.方法 将399例患者随机分为3组.(1)32P胶体治疗组:100例,男37例,女63例.取32P 0.37～0.74 MBq/cm3,2%利多卡因0.5 ml,生理盐水适量,配成混合液行瘤体内多点注射,2周1次,2次为1个疗程.(2)平阳霉素治疗组:99例,男30例,女69例.取平阳霉素1 mg/cm3,2%利多卡因0.5 ml,生理盐水适量,配成混合液于瘤体内多点注射,方法同上.(3)32P胶体加平阳霉素治疗组:200例,男64例,女136例.取32P 0.25 MBq/cm3,平阳霉素0.5 mg/cm3,2%利多卡因0.5 ml,生理盐水适量,配成混合液于瘤体内多点注射,方法同上.结果 32P胶体加平阳霉素治疗组治愈率88.5%;32P胶体治疗组治愈率77.0%;平阳霉素治疗组治愈率71.7%.3种方法的有效率差异有统计学意义(P＜0.05).结论 32P胶体、平阳霉素、32P加阳霉素治疗血管瘤均有疗效,但32P胶体加平阳霉素联合治疗血管瘤作用强,剂量小于单独使用,且方法简便易行,安全可靠,并发症少.
目的 探討和評價小劑量32P和平暘黴素聯閤治療嬰幼兒頜麵部血管瘤的療效.方法 將399例患者隨機分為3組.(1)32P膠體治療組:100例,男37例,女63例.取32P 0.37～0.74 MBq/cm3,2%利多卡因0.5 ml,生理鹽水適量,配成混閤液行瘤體內多點註射,2週1次,2次為1箇療程.(2)平暘黴素治療組:99例,男30例,女69例.取平暘黴素1 mg/cm3,2%利多卡因0.5 ml,生理鹽水適量,配成混閤液于瘤體內多點註射,方法同上.(3)32P膠體加平暘黴素治療組:200例,男64例,女136例.取32P 0.25 MBq/cm3,平暘黴素0.5 mg/cm3,2%利多卡因0.5 ml,生理鹽水適量,配成混閤液于瘤體內多點註射,方法同上.結果 32P膠體加平暘黴素治療組治愈率88.5%;32P膠體治療組治愈率77.0%;平暘黴素治療組治愈率71.7%.3種方法的有效率差異有統計學意義(P＜0.05).結論 32P膠體、平暘黴素、32P加暘黴素治療血管瘤均有療效,但32P膠體加平暘黴素聯閤治療血管瘤作用彊,劑量小于單獨使用,且方法簡便易行,安全可靠,併髮癥少.
목적 탐토화평개소제량32P화평양매소연합치료영유인합면부혈관류적료효.방법 장399례환자수궤분위3조.(1)32P효체치료조:100례,남37례,녀63례.취32P 0.37～0.74 MBq/cm3,2%리다잡인0.5 ml,생리염수괄량,배성혼합액행류체내다점주사,2주1차,2차위1개료정.(2)평양매소치료조:99례,남30례,녀69례.취평양매소1 mg/cm3,2%리다잡인0.5 ml,생리염수괄량,배성혼합액우류체내다점주사,방법동상.(3)32P효체가평양매소치료조:200례,남64례,녀136례.취32P 0.25 MBq/cm3,평양매소0.5 mg/cm3,2%리다잡인0.5 ml,생리염수괄량,배성혼합액우류체내다점주사,방법동상.결과 32P효체가평양매소치료조치유솔88.5%;32P효체치료조치유솔77.0%;평양매소치료조치유솔71.7%.3충방법적유효솔차이유통계학의의(P＜0.05).결론 32P효체、평양매소、32P가양매소치료혈관류균유료효,단32P효체가평양매소연합치료혈관류작용강,제량소우단독사용,차방법간편역행,안전가고,병발증소.
Objective To explore and evaluate the effect of 32P and pinyangmycin injected in combination for the treatment of maxillofacial hemangioma. Methods The patients were randomly divided into three groups. The first group of patients was treated with 32P; 100 patients were enrolled in this group, of which 37 were male and 63 female. 32P dosage between 0.37 and 0. 74 MBq per cm3 was prepared together with 0.5 ml of 2 %lidocaine, and appropriate normal saline, and then the mixture was injected into hemangioma every two weeks. The second group was given pinyangmycin, and the third group received both 32P and pinyangmycin. The second group included 30 male and 60 female, and the third group 64 male and 136 female. The dose and frequency were given as the same to the first group. Results 88.5 % of patients were cured using both 32P and pinyangmycin, and the cure rate was 77.0 % and 71.7 % with either 32P or pinyangmycin. Conclusion These results prove that 32P and pinyangmycin injected in combination for the treatment of maxillofacial hemangioma is more effective than either 32P or pinyangmycin alone, and furthermore, the method is easy, safe and has less complications.
