中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2009年
4期
401-404
,共4页
孙涛%卢洁%尹勇%刘同海%陈进琥%林秀桐%朱健%白瞳%刘波
孫濤%盧潔%尹勇%劉同海%陳進琥%林秀桐%硃健%白瞳%劉波
손도%로길%윤용%류동해%진진호%림수동%주건%백동%류파
乳腺肿瘤%乳房保留术%正向调强放射治疗%逆向调强放射治疗
乳腺腫瘤%乳房保留術%正嚮調彊放射治療%逆嚮調彊放射治療
유선종류%유방보류술%정향조강방사치료%역향조강방사치료
Breast neoplasm%Breast-conservative surgery%Forward intensity-modulated radiotherapy%Inverse intensity-modulated radiotherapy
目的 比较乳腺癌调强放疗计划的正向和逆向2种设计模式的区别.方法 针对6例左侧乳腺癌保乳术后的患者应用Pinnacle3 7.4f计划系统,分别设计正向和逆向调强放疗计划,在射野方向相同、保证处方剂量线包绕95%靶区体积的前提下,比较2种计划的剂量体积直方图参数和加速器总跳数.结果 2种调强计划相比,正向及逆向调强计划的计划靶区体积适形度指数值分别为0.67±0.06和0.66±0.06(t=2.423,P＞0.05),均匀性指数值分别为(28.2±6.0)%和(26.1±6.8)%(t=2.164,P＞0.05);左肺V20分别为(18.7±3.3)%和(17.0±2.8)%(t=5.087,P<0.05),V30分别为(15.5±3.0)%和(14.0±2.6)%(t=7.272,P<0.05);心脏V30分别为(4.1±3.1)%和(3.5±2.5)%(t=1.916,P＞0.05);机器跳数分别为(262±5)MU和(308±14)MU(t=7.515,P<0.05).结论 与正向调强放疗计划相比,乳腺癌逆向调强计划中靶区适形度和均匀性无差别,左肺受量降低,心脏受量无差别;但机器跳数显著增加,增加了机器的磨损和治疗实施时间.
目的 比較乳腺癌調彊放療計劃的正嚮和逆嚮2種設計模式的區彆.方法 針對6例左側乳腺癌保乳術後的患者應用Pinnacle3 7.4f計劃繫統,分彆設計正嚮和逆嚮調彊放療計劃,在射野方嚮相同、保證處方劑量線包繞95%靶區體積的前提下,比較2種計劃的劑量體積直方圖參數和加速器總跳數.結果 2種調彊計劃相比,正嚮及逆嚮調彊計劃的計劃靶區體積適形度指數值分彆為0.67±0.06和0.66±0.06(t=2.423,P＞0.05),均勻性指數值分彆為(28.2±6.0)%和(26.1±6.8)%(t=2.164,P＞0.05);左肺V20分彆為(18.7±3.3)%和(17.0±2.8)%(t=5.087,P<0.05),V30分彆為(15.5±3.0)%和(14.0±2.6)%(t=7.272,P<0.05);心髒V30分彆為(4.1±3.1)%和(3.5±2.5)%(t=1.916,P＞0.05);機器跳數分彆為(262±5)MU和(308±14)MU(t=7.515,P<0.05).結論 與正嚮調彊放療計劃相比,乳腺癌逆嚮調彊計劃中靶區適形度和均勻性無差彆,左肺受量降低,心髒受量無差彆;但機器跳數顯著增加,增加瞭機器的磨損和治療實施時間.
목적 비교유선암조강방료계화적정향화역향2충설계모식적구별.방법 침대6례좌측유선암보유술후적환자응용Pinnacle3 7.4f계화계통,분별설계정향화역향조강방료계화,재사야방향상동、보증처방제량선포요95%파구체적적전제하,비교2충계화적제량체적직방도삼수화가속기총도수.결과 2충조강계화상비,정향급역향조강계화적계화파구체적괄형도지수치분별위0.67±0.06화0.66±0.06(t=2.423,P＞0.05),균균성지수치분별위(28.2±6.0)%화(26.1±6.8)%(t=2.164,P＞0.05);좌폐V20분별위(18.7±3.3)%화(17.0±2.8)%(t=5.087,P<0.05),V30분별위(15.5±3.0)%화(14.0±2.6)%(t=7.272,P<0.05);심장V30분별위(4.1±3.1)%화(3.5±2.5)%(t=1.916,P＞0.05);궤기도수분별위(262±5)MU화(308±14)MU(t=7.515,P<0.05).결론 여정향조강방료계화상비,유선암역향조강계화중파구괄형도화균균성무차별,좌폐수량강저,심장수량무차별;단궤기도수현저증가,증가료궤기적마손화치료실시시간.
Objective To compare the dosimetric difference in forward intensity modulation radiotherapy (fIMRT)and inverse IMRT(iIMRT)planning for breast cancer.Methods Six patients received radiotherapy alone after left breast-conserving surgery were selected.For each patient,two treatment phns(flMRT and iIMRT)were designed with Pinnacle3 7.4f.In each plan,the volume of PIT received prescription dose was not less than 95 %.The dosimetrie parameters were assessed with dose volume histograms in planning target volume (PIT)and organ of around risk(OAR).Results Of flMRT and ilMRT plans,the PTV average canformal indexwere(0.67±0.06)and(0.66±0.06)(t = 2.423,P ＞ 0.05),average homogeneity index were (28.2±6.0)% and(26.1±6.8)%(t = 2.164,P ＞ 0.05);the volume of left lung received 20 Gy(V20)were(18.7±3.3)% and(17.0±2.8)%(t =5.087,P<0.05),and V30 of left lung were(15.5±3.0)%and(14.0±2.6)%(t =7.272,P<0.05);V30 of heart were(4.1±3.1)% and(3.5±2.5)%(t=1.916,P ＞ 0.05);the total monitor units were(262±5)MU and(308±14)MU(t = 7.515,P < 0.05).Conclusions There were no significant differences of CI,HI,and V30 of heart between flMRT and iIMRT.Because of fewer MUs,fIMRT plan could reduce the machine abrasion and treatment time,but V30 and V30 of left lung are higher significantly than iIMRT plan.
