中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
2期
156-157
,共2页
镇痛,产科%妇科外科手术%甲磺酸罗哌卡因
鎮痛,產科%婦科外科手術%甲磺痠囉哌卡因
진통,산과%부과외과수술%갑광산라고잡인
Analgesia,obstetrical%Gynecologic surgical procedures%Ropivacaine
目的 观察甲磺酸罗哌卡因单次硬膜外腔注射用于妇产科手术后镇痛的临床效果.方法 180例妇产科手术患者随机分为两组:治疗组在手术缝皮肤时通过硬膜外腔一次注射镇痛液(罗哌卡因+吗啡),对照组在手术缝皮肤时注人镇痛液5~6 ml后接自控式镇痛泵,观察两组血流动力学、心率变化情况及术后48 h镇痛效果、不良反发生率等.结果 两组镇痛前后平均动脉压、血氧饱和度、心率比较,差异无统计学意义(均P>0.05);治疗组术后24 h、48 h镇痛效果0级(无痛率)均明显高于对照组(χ~2=3.9.74、4.031,均P<0.05);两组未发生严重不良反应.结论 申磺酸罗哌卡因单次硬膜外腔注射用于妇产科术后镇痛效果好、不良反应少.
目的 觀察甲磺痠囉哌卡因單次硬膜外腔註射用于婦產科手術後鎮痛的臨床效果.方法 180例婦產科手術患者隨機分為兩組:治療組在手術縫皮膚時通過硬膜外腔一次註射鎮痛液(囉哌卡因+嗎啡),對照組在手術縫皮膚時註人鎮痛液5~6 ml後接自控式鎮痛泵,觀察兩組血流動力學、心率變化情況及術後48 h鎮痛效果、不良反髮生率等.結果 兩組鎮痛前後平均動脈壓、血氧飽和度、心率比較,差異無統計學意義(均P>0.05);治療組術後24 h、48 h鎮痛效果0級(無痛率)均明顯高于對照組(χ~2=3.9.74、4.031,均P<0.05);兩組未髮生嚴重不良反應.結論 申磺痠囉哌卡因單次硬膜外腔註射用于婦產科術後鎮痛效果好、不良反應少.
목적 관찰갑광산라고잡인단차경막외강주사용우부산과수술후진통적림상효과.방법 180례부산과수술환자수궤분위량조:치료조재수술봉피부시통과경막외강일차주사진통액(라고잡인+마배),대조조재수술봉피부시주인진통액5~6 ml후접자공식진통빙,관찰량조혈류동역학、심솔변화정황급술후48 h진통효과、불량반발생솔등.결과 량조진통전후평균동맥압、혈양포화도、심솔비교,차이무통계학의의(균P>0.05);치료조술후24 h、48 h진통효과0급(무통솔)균명현고우대조조(χ~2=3.9.74、4.031,균P<0.05);량조미발생엄중불량반응.결론 신광산라고잡인단차경막외강주사용우부산과술후진통효과호、불량반응소.
Objective To observe the clinical effect of using single epidural injection of S-Ropivacaine Mesylate to ease the pain after gynaecology and obstetrics operations.Methods 180 patients who need gynaecological operations were randomly divided into two groups.The group of therapy was injected the analgesic(ropivacaine + morphia)at once when suturing the skin.And the comparing group only injected 5~6ml of analgesic at the stage of skin suture,then selfoperated analgesia pump will be used.The changes of hemodynamics and SpO_2 pf the two groups,the analgesic activities after 48 hours,occurrence of adverse reaction,etc were analyzed.Results The differences of MAP,SpO_2,and HR had statistical significance(P>0.05);After the surgery,the effept of analgesic of 24h and 48h grade 0(pain-free rate)in therapy group is much more obvious than comparing group(χ~2=3.974,4.031,P<0.05);Neither group has severe adverse reaction.Conclusion The effect of using sihgle epidural injection of S-Ropivacaine Mesylate to ease the pain after gynaecology and obstetrics surgeries is gopd,and has little adverse reaction.