CAJ | 학술논문

金黄色葡萄球菌(金葡菌)目前仍是医院内感染的主要病原菌之一,我们的资料显示上海地区1977～1979年和1985～1986年甲氧西林耐药金葡菌(MRSA)分别为同时期金葡菌的5%和24%.绝大部份的MRSA菌株对青霉素G四环素、强力霉素、红霉素和庆大霉素耐药;对头孢菌素类大多呈中度或轻度敏感,但对头孢孟多敏感.MRSA菌株对万古霉素、褐霉素、壁霉素、丙氟哌酸和香豆霉素呈高度敏感;利福平和复方SMZ对MRSA菌株亦具有良好的抗菌活性.建议在临床各医院细菌科采用苯唑青霉素纸片代替甲氧西林检测和控制MRSA在我国的流行.
금황색포도구균(금포균)목전잉시의원내감염적주요병원균지일,아문적자료현시상해지구1977～1979년화1985～1986년갑양서림내약금포균(MRSA)분별위동시기금포균적5%화24%.절대부빈적MRSA균주대청매소G사배소、강력매소、홍매소화경대매소내약;대두포균소류대다정중도혹경도민감,단대두포맹다민감.MRSA균주대만고매소、갈매소、벽매소、병불고산화향두매소정고도민감;리복평화복방SMZ대MRSA균주역구유량호적항균활성.건의재림상각의원세균과채용분서청매소지편대체갑양서림검측화공제MRSA재아국적류행.
S.aurous is still one of the common pathogens of serious infections in hospitals.it accounts for about one third of the etiological agents of baeremia in this country.Our data show that methicillin resistant Staphylococcus aureus(MRSA)accounted for 5% and 24% in S.aureus population isola Sed in 1977～79 and 1985～86 respectively in Shanghai hospitals.Most strains are resistant to penicillin G,tetracycline, doxyeycline, erythromyain and gentamycin,moderately or slightly sensitive to cephalosporine(usually highly sensitive to cefamandole);highly sensitive to vancomycin f fusidin.teichoplanin,ciprofloxacin and coumermycin and fairly susceptible 40 refampicin and cotrimoxazole.Factors influencing methicillin resistance of S.sureus are discussed.A routine test using oxacillin disks under modified conditions for the detection of MRSA is suggesled.