CAJ | 학술논문

目的提高对肺炎支原体(MP)感染的临床认识,合理诊治MP,合理使用抗生素以减少耐药性的发生.方法对2005年3月至2008年2月上海第八人民医院收治的136例下呼吸道肺炎支原体感染病例,对其临床过程、实验室检查和治疗措施进行总结和分析.结果发病年龄多为学龄儿,早期无明显阳性体征,MP痰液培养阳性率低,仅占3.9%;外周血白细胞多正常,占70.6%;但CRP升高,占44.1%;胸片表现有多样性,30例有不同程度肺外表现,其中主要是渗出性胸膜炎,占13.2%.治疗用阿奇霉素效果良好,总有效率达96.7%.结论 MP感染好发于学龄儿,MP-IgM阳性率高,占85.3%.阿奇霉素治疗疗程短、疗效好.对MP感染应尽量做到早期诊断,合理使用大环内酯类抗生素,并加强对MP感染耐药性的检测有非常重要的现实意义.
목적 제고대폐염지원체(MP)감염적림상인식,합리진치MP,합리사용항생소이감소내약성적발생.방법 대2005년3월지2008년2월상해제팔인민의원수치적136례하호흡도폐염지원체감염병례,대기림상과정、실험실검사화치료조시진행총결화분석.결과발병년령다위학령인,조기무명현양성체정,MP담액배양양성솔저,부점3.9%;외주혈백세포다정상,점70.6%;단CRP승고,점44.1%;흉편표현유다양성,30례유불동정도폐외표현,기중주요시삼출성흉막염,점13.2%.치료용아기매소효과량호,총유효솔체96.7%.결론 MP감염호발우학령인,MP-IgM양성솔고,점85.3%.아기매소치료료정단、료효호.대MP감염응진량주도조기진단,합리사용대배내지류항생소,병가강대MP감염내약성적검측유비상중요적현실의의.
Objective Enrich knowledge of Mycoplasma pneumoniae infection;try to find the best way to therapy and diagnosis MP, and how to use antibiotics rationally to reduce the antibiotics resistance. Methods Collected 136 cases of MP infection in lower respiratory of children.The clinical course,laboratory investigation, therapy of these patients were retrospectively reviewed and analysis. Results School-age children were more like to get the disease. This disease has no obviously positive characteristics earlier. MP were isolated and identified. There were lower positive rate in spittle culture,only being 3.9%.Most of them the WBC of blood were in normal level,being 70. 6%But the CRP were rise,being 40.1%.The X-rays were various. 30 cases out of 136 had medical complications out of the lungs. There were higher response of using azithromycin, being 96.7%. ConclusionMP infect often occur to school-age children. And the positive rate of MP-IgM was higher,being 85.3%. Usage of asithromycin can reduce the course of treatment,and the function curative effect was better. But we should diagnosis MP as passible as earlier,and use macrolides antibiotics rationally; there are very important realistic significance to strengthen to check of the antibiotic resistance of MP infection.