CAJ | 학술논문

目的探讨糖尿病酮症酸中毒患者口腔菌群的改变,为糖尿病患者制订口腔护理干预和口腔卫生宣教提供理论依据.方法糖尿病酮症酸中毒患者35例(A组),同时选择35例非糖尿病慢性牙周炎(诊断标准:患牙牙周袋＞14 mm)患者(B组)和35例糖尿病非酮症患者(C组)作为对照组,检查记录口腔疾病状况,评估口腔卫生状况.结果 3组牙龈指数、菌斑指数、牙齿松动、探诊深度、探诊后出血情况比较,均无显著差异;3组口腔链球菌、口腔乳杆菌、核梭杆菌、产黑菌、二氧化碳噬纤维菌无显著差异,放线菌、大肠埃希菌、金黄色葡萄球菌、铜绿假单胞菌、肺炎克雷伯菌、鲍曼复合醋酸钙不动杆菌、白假丝酵母菌的检出率均有显著差异;产黑菌、二氧化碳噬纤维菌数量与糖尿病酮症酸中毒患者的空腹血糖值、糖化血红蛋白之间存在正相关关系.结论糖尿病酮症酸中毒加大了患者日腔细菌侵袭和定植.
목적 탐토당뇨병동증산중독환자구강균군적개변,위당뇨병환자제정구강호리간예화구강위생선교제공이론의거.방법 당뇨병동증산중독환자35례(A조),동시선택35례비당뇨병만성아주염(진단표준:환아아주대＞14 mm)환자(B조)화35례당뇨병비동증환자(C조)작위대조조,검사기록구강질병상황,평고구강위생상황.결과 3조아간지수、균반지수、아치송동、탐진심도、탐진후출혈정황비교,균무현저차이;3조구강련구균、구강유간균、핵사간균、산흑균、이양화탄서섬유균무현저차이,방선균、대장애희균、금황색포도구균、동록가단포균、폐염극뢰백균、포만복합작산개불동간균、백가사효모균적검출솔균유현저차이;산흑균、이양화탄서섬유균수량여당뇨병동증산중독환자적공복혈당치、당화혈홍단백지간존재정상관관계.결론 당뇨병동증산중독가대료환자일강세균침습화정식.
Objective To study the changes of oral flora in patients with diabetic ketoacidosis,in order to provide evidence for making oral nursing intervention and hygiene education. Methods 35 patients with diabetic ketoacidosis were named as group A,35 non-diabetic patients with chronic periodontitis (diagnostic criteria:periodontal pocket 14 mm) were named as group B,35 nonketotic patients with diabetes mellitus were named as group C,then all the patients were detected for the oral disease and the oral hygiene was evaluated. Results The gingival index,plaque index,tooth mobility,probing depth and hemorrhage after the detection of three groups had no significant differences. The detection rate of streptococcus oralis, lactobacillus,fusobacterium nucleatum,black-pigment bacteria,Capnocytophaga gingivalis,actinomycetes, escherichia coli,staphylococcus aureus and pseudomonas aeruginosa had no significant differences,there was a positive correlation between quantity of black-pigment bacteria, Capnocytophaga gingivalis and fasting blood glucose and glycosylated hemoglobin of patients with diabetic ketoacidosis. Conclusions Diabetic ketoacidosis strengthened the bacterial invasion and oral colonization of patients.