科技通报
科技通報
과기통보
BULLETIN OF SCIENCE AND TECHNOLOGY
2001年
4期
73-75
,共3页
董兴刚%安增梅%杨海春%周江华%殷祥雷%顾建新
董興剛%安增梅%楊海春%週江華%慇祥雷%顧建新
동흥강%안증매%양해춘%주강화%은상뢰%고건신
带蒂大网膜包肾%肾小球硬化%蛋白尿
帶蒂大網膜包腎%腎小毬硬化%蛋白尿
대체대망막포신%신소구경화%단백뇨
为探讨带蒂大网膜包肾术防治肾小球硬化的作用。采用单侧肾切除加二次注射阿霉素制备的肾小球硬化动物模型,观察带蒂大网膜包肾对肾脏的作用。结果表明,带蒂大网膜包肾可降低血胆固醇、甘油三脂,尿蛋白排泄,肾小球球囊粘连减轻。血尿素氮有下降趋势。说明带蒂大网膜包肾术对肾小球硬化大鼠的肾脏损伤有保护作用。
為探討帶蒂大網膜包腎術防治腎小毬硬化的作用。採用單側腎切除加二次註射阿黴素製備的腎小毬硬化動物模型,觀察帶蒂大網膜包腎對腎髒的作用。結果錶明,帶蒂大網膜包腎可降低血膽固醇、甘油三脂,尿蛋白排洩,腎小毬毬囊粘連減輕。血尿素氮有下降趨勢。說明帶蒂大網膜包腎術對腎小毬硬化大鼠的腎髒損傷有保護作用。
위탐토대체대망막포신술방치신소구경화적작용。채용단측신절제가이차주사아매소제비적신소구경화동물모형,관찰대체대망막포신대신장적작용。결과표명,대체대망막포신가강저혈담고순、감유삼지,뇨단백배설,신소구구낭점련감경。혈뇨소담유하강추세。설명대체대망막포신술대신소구경화대서적신장손상유보호작용。
To investigate the protective effects of pedicled omental transposition on the kidney with glomerulosclerosis.Uninephrectomized rats were divided into two groups.Normal rats were put in the blank control group,glomerulosclerosis rats by adriamycin were divided into glomerulosclerosis group and pedicled omental transposition group.Serum lipids,urea and urinary protein were assayed. Renal histological examination was also performed. Results showed that pedicled omental transposition could not only reduced the serum levels of total cholesterol and triglyceride, but also decrease the accumulation of extracellular matrix (P<0.05).Conclusions pedicled omental transposition has the effect of attenuating renal damage in rats with glomerulosclerosis.