中国神经精神疾病杂志
中國神經精神疾病雜誌
중국신경정신질병잡지
CHINESE JOURNAL OF NERVOUS AND MENTAL DISEASES
2010年
2期
92-95
,共4页
资文杰%杨燕%段大志%帅杰
資文傑%楊燕%段大誌%帥傑
자문걸%양연%단대지%수걸
多模式CT%灌注CT达峰时间%支架置入术
多模式CT%灌註CT達峰時間%支架置入術
다모식CT%관주CT체봉시간%지가치입술
Cerebral arterical disease CT perfusion%Time to peak(TTP)%Stent
目的 应用MOSAIC评分系统研究缺血性脑血管病患者支架置入术治疗的获益程度.方法 在本院行大脑中动脉/颈内动脉支架置入术的脑血管病患者26例, 使用MOSAIC(multimodal stroke assessment using computed tomography)评分系统对患者术前神经影像资料进行评分,并同时用ASPECTS (Alberta stroke program early CT score)对患者手术前后头颅灌注CT情况进行评分, 并对两者间的相关性进行分析.结果 26例患者术前MOSAIC评分分为4组,4分组6例、5分组7例、6分组6例、7分组7例,4组病例经ASPECTS量表评分后的TTP改善程度分别为31.7%±14.17%、38.6%±15.73%、43.3%±10.33%、58.6%±13.45%,差异有统计学意义( H=10.673,P <0.05).对患者术前MOSAIC评分与支架置入术后TTP改善程度进行相关性分析,两者之间呈正相关( r=0.579,P <0.002).结论 在多模式CT的基础上使用MOSAIC评分可以对支架置入术前患者的神经血管病理影像进行定量评价,MOSAIC评分越高的患者,支架置入术后TTP改善程度越好,支架治疗的获益程度更大.
目的 應用MOSAIC評分繫統研究缺血性腦血管病患者支架置入術治療的穫益程度.方法 在本院行大腦中動脈/頸內動脈支架置入術的腦血管病患者26例, 使用MOSAIC(multimodal stroke assessment using computed tomography)評分繫統對患者術前神經影像資料進行評分,併同時用ASPECTS (Alberta stroke program early CT score)對患者手術前後頭顱灌註CT情況進行評分, 併對兩者間的相關性進行分析.結果 26例患者術前MOSAIC評分分為4組,4分組6例、5分組7例、6分組6例、7分組7例,4組病例經ASPECTS量錶評分後的TTP改善程度分彆為31.7%±14.17%、38.6%±15.73%、43.3%±10.33%、58.6%±13.45%,差異有統計學意義( H=10.673,P <0.05).對患者術前MOSAIC評分與支架置入術後TTP改善程度進行相關性分析,兩者之間呈正相關( r=0.579,P <0.002).結論 在多模式CT的基礎上使用MOSAIC評分可以對支架置入術前患者的神經血管病理影像進行定量評價,MOSAIC評分越高的患者,支架置入術後TTP改善程度越好,支架治療的穫益程度更大.
목적 응용MOSAIC평분계통연구결혈성뇌혈관병환자지가치입술치료적획익정도.방법 재본원행대뇌중동맥/경내동맥지가치입술적뇌혈관병환자26례, 사용MOSAIC(multimodal stroke assessment using computed tomography)평분계통대환자술전신경영상자료진행평분,병동시용ASPECTS (Alberta stroke program early CT score)대환자수술전후두로관주CT정황진행평분, 병대량자간적상관성진행분석.결과 26례환자술전MOSAIC평분분위4조,4분조6례、5분조7례、6분조6례、7분조7례,4조병례경ASPECTS량표평분후적TTP개선정도분별위31.7%±14.17%、38.6%±15.73%、43.3%±10.33%、58.6%±13.45%,차이유통계학의의( H=10.673,P <0.05).대환자술전MOSAIC평분여지가치입술후TTP개선정도진행상관성분석,량자지간정정상관( r=0.579,P <0.002).결론 재다모식CT적기출상사용MOSAIC평분가이대지가치입술전환자적신경혈관병리영상진행정량평개,MOSAIC평분월고적환자,지가치입술후TTP개선정도월호,지가치료적획익정도경대.
Objective To evaluate the effect of stent implantation using Multimodal CT in patients with MCA and ICA stenosis. Methods Twenty-six patients with ischemic cerebrovascular disease who received MCA or ICA stent implantation in ChongQing xinqiao Hospital were recruited. Multimodal Stroke Assessment Using CT Score (MOSAIC) was used to evaluate the Neuroimaging data before stent implantation and Alberta Stroke Program Early CT Score (ASPECTS) to evaluate the time to peak (TTP) of CTP before and after stent implantation. Results Patients were divided into 4 groups based on scores: 4 scores, 5 scores, 6 scores, and 7 scores groups. the improvement degree was increase by 31.7%±14.17%、38.6%±15.73%、43.3%±10.3%、358.6%±13.45% in 4 scores, 5 scores, 6 scores, and 7 scores groups, respectively. The paired t test demonstrated that there were a statistically significant difference among four groups(H=10.673, P <0.05). Preoperative MOSAIC score was positively correlated with the improvement of ASPECT score for TTP, with a correlation coefficient of 0.579 ( P <0.002). Conclusions Multimodal CT is a sensitive assessment for the evaluation of ischemic cerebrovascular disease and patients with a higher MOSAIC score may benefit more from stent implantation.