中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
14期
2087-2089
,共3页
磁共振成像,弥散%乳腺肿瘤
磁共振成像,瀰散%乳腺腫瘤
자공진성상,미산%유선종류
Diffusion magnetic resonance imaging%Breast neoplasms
目的 探讨磁共振扩散加权成像(DWI)的表观扩散系数(ADC)值对乳腺肿块鉴别诊断价值,提高乳腺癌的诊断特异性.方法 对93例105个乳腺肿块患者行常规MR平扫DWI成像,测量ADC值.结果 37例43个良性病灶的平均ADC值:(1.37±0.36)×10-3 mm2/s,最大、最小ADC差值(0.63±0.19)×10-3mm2/s;58例62个恶性病灶的平均ADC值:(0.90±0.53)×10-3mm2/s,最大、最小ADC差值(0.91±0.27)×10-3 mm2/s;两者平均ADC值,最大、最小ADC差值的差异均有统计学意义(均P<0.01).绘制诊断良、恶性病变ADC值ROC曲线,以1.1×10-3mm2/s作为临界值作为判断良、恶性的标准,敏感性为67%,特异性为72%;以1.0×10-3mm2/s为临界值,特异性可提高到84%.而敏感度降为60%.以最大、最小ADC差值0.75×10-3mm2/s为临界值,敏感性为67%,特异性为68%,如以0.80×10-3mm2/s为临界值,敏感性为53%,特异性为82%.结论 DWI的ADC值对乳腺良恶性病变的鉴别诊断具有一定的意义.
目的 探討磁共振擴散加權成像(DWI)的錶觀擴散繫數(ADC)值對乳腺腫塊鑒彆診斷價值,提高乳腺癌的診斷特異性.方法 對93例105箇乳腺腫塊患者行常規MR平掃DWI成像,測量ADC值.結果 37例43箇良性病竈的平均ADC值:(1.37±0.36)×10-3 mm2/s,最大、最小ADC差值(0.63±0.19)×10-3mm2/s;58例62箇噁性病竈的平均ADC值:(0.90±0.53)×10-3mm2/s,最大、最小ADC差值(0.91±0.27)×10-3 mm2/s;兩者平均ADC值,最大、最小ADC差值的差異均有統計學意義(均P<0.01).繪製診斷良、噁性病變ADC值ROC麯線,以1.1×10-3mm2/s作為臨界值作為判斷良、噁性的標準,敏感性為67%,特異性為72%;以1.0×10-3mm2/s為臨界值,特異性可提高到84%.而敏感度降為60%.以最大、最小ADC差值0.75×10-3mm2/s為臨界值,敏感性為67%,特異性為68%,如以0.80×10-3mm2/s為臨界值,敏感性為53%,特異性為82%.結論 DWI的ADC值對乳腺良噁性病變的鑒彆診斷具有一定的意義.
목적 탐토자공진확산가권성상(DWI)적표관확산계수(ADC)치대유선종괴감별진단개치,제고유선암적진단특이성.방법 대93례105개유선종괴환자행상규MR평소DWI성상,측량ADC치.결과 37례43개량성병조적평균ADC치:(1.37±0.36)×10-3 mm2/s,최대、최소ADC차치(0.63±0.19)×10-3mm2/s;58례62개악성병조적평균ADC치:(0.90±0.53)×10-3mm2/s,최대、최소ADC차치(0.91±0.27)×10-3 mm2/s;량자평균ADC치,최대、최소ADC차치적차이균유통계학의의(균P<0.01).회제진단량、악성병변ADC치ROC곡선,이1.1×10-3mm2/s작위림계치작위판단량、악성적표준,민감성위67%,특이성위72%;이1.0×10-3mm2/s위림계치,특이성가제고도84%.이민감도강위60%.이최대、최소ADC차치0.75×10-3mm2/s위림계치,민감성위67%,특이성위68%,여이0.80×10-3mm2/s위림계치,민감성위53%,특이성위82%.결론 DWI적ADC치대유선량악성병변적감별진단구유일정적의의.
Objective To explore the differential diagnosis value of DWI ADC for breast lumps,improve the diagnosis of breast cancer specificity.Methods 93 patients with 105 breast tumors were performed with routine MR series and DWI,and the ADC values were measured.Results Lesions ADC values:average ADC value 43 benign lesions in 37 cases was(1.37±0.36)×10-3 mm2/s,the different value between max and min was(0.63±0.19)×10 -3s/mm2.Average ADC value of 62 malignant lesions in 58 patients was(0.90±0.53) × 10 -3 mm2/s,the different value between max and min was(0.91±0.27)×10-3 mm2/s.By statistical analysis,both average ADC values and the max and the min ADC difference value were very significantly different(P<0.01).Draw diagnosis benign and malignant lesions ROC curves,with ADC values 0.11×10 -3 mm2/s for critical value to judge benign and malignant standard,sensitivity was 67%,specificity was 72%.With 1.0×10- 3 mm2/s for critical value,specificity can raise to 84%,and sensitivity came to 60%.With the maximum and minimum ADC difference value 0.75 × 10-3s/mm2 for critical value,sensitivity was 67%,specificity was 68%.If with 0.80 for critical value,sensitivity was 53% and specificity 82%.Conclusion The average ADC values of DWI were significant for the identification of benign and malignant lesions.