中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2009年
7期
436-439
,共4页
车春晖%黄华品%刘昌云%江芳%陈晓春
車春暉%黃華品%劉昌雲%江芳%陳曉春
차춘휘%황화품%류창운%강방%진효춘
癫(癎)%生活质量%抑郁%焦虑
癲(癎)%生活質量%抑鬱%焦慮
전(간)%생활질량%억욱%초필
Eepilepsy%Quality of life%Depression%Anxiety
目的 调查癫(癎)患者健康相关生存质量和情绪健康状况,探讨各种因素对患者生存质量的影响.方法 使用世界卫生组织(WHO)生存质量量表中文版简表(QOL-BREF)附加癫(癎)生存质量量表(QOLIE)-31(中文版)、抑郁自评量表(SD5)、焦虑自评量表(SAS)进行生存质量和心境健康状况调查.多元逐步回归分析各种因素对生存质量的影响.结果 癫(癎)患者(n=141)在WHOQOL-BREF的生理、心理领域得分(分别为12.7±1.8、12.4 4-1.9)比常模下降(15.1±2.3、13.9±1.9,t=11.75、8.625,P<0.05);有抑郁情绪者占57.4 % ,有焦虑情绪者占39.7 % .合并抑郁、焦虑情绪的癫(癎)患者在除外QOLIE-31药物的影响领域的生存质量各个领域得分均减低;多元逐步回归结果显示,影响QOLIE总分的3个因素按影响作用大小依次是焦虑、抑郁和病程.结论 合并抑郁、焦虑情绪障碍,病程长是癫(癎)患者生存质量下降的重要因素.
目的 調查癲(癎)患者健康相關生存質量和情緒健康狀況,探討各種因素對患者生存質量的影響.方法 使用世界衛生組織(WHO)生存質量量錶中文版簡錶(QOL-BREF)附加癲(癎)生存質量量錶(QOLIE)-31(中文版)、抑鬱自評量錶(SD5)、焦慮自評量錶(SAS)進行生存質量和心境健康狀況調查.多元逐步迴歸分析各種因素對生存質量的影響.結果 癲(癎)患者(n=141)在WHOQOL-BREF的生理、心理領域得分(分彆為12.7±1.8、12.4 4-1.9)比常模下降(15.1±2.3、13.9±1.9,t=11.75、8.625,P<0.05);有抑鬱情緒者佔57.4 % ,有焦慮情緒者佔39.7 % .閤併抑鬱、焦慮情緒的癲(癎)患者在除外QOLIE-31藥物的影響領域的生存質量各箇領域得分均減低;多元逐步迴歸結果顯示,影響QOLIE總分的3箇因素按影響作用大小依次是焦慮、抑鬱和病程.結論 閤併抑鬱、焦慮情緒障礙,病程長是癲(癎)患者生存質量下降的重要因素.
목적 조사전(간)환자건강상관생존질량화정서건강상황,탐토각충인소대환자생존질량적영향.방법 사용세계위생조직(WHO)생존질량량표중문판간표(QOL-BREF)부가전(간)생존질량량표(QOLIE)-31(중문판)、억욱자평량표(SD5)、초필자평량표(SAS)진행생존질량화심경건강상황조사.다원축보회귀분석각충인소대생존질량적영향.결과 전(간)환자(n=141)재WHOQOL-BREF적생리、심리영역득분(분별위12.7±1.8、12.4 4-1.9)비상모하강(15.1±2.3、13.9±1.9,t=11.75、8.625,P<0.05);유억욱정서자점57.4 % ,유초필정서자점39.7 % .합병억욱、초필정서적전(간)환자재제외QOLIE-31약물적영향영역적생존질량각개영역득분균감저;다원축보회귀결과현시,영향QOLIE총분적3개인소안영향작용대소의차시초필、억욱화병정.결론 합병억욱、초필정서장애,병정장시전(간)환자생존질량하강적중요인소.
Objective To assess health-related quality of life and the mood disorder in adults with epilepsy,and to evaluate factors contributing to the quality of life.Methods Quality of life was measured by the Quality of Life in Epilepsy Inventory(QOLIE-31)and the World Health Organization Quality of Life Assessment-Bref(WHOQOL-BREF).Psychotic conditions were evaluated by Self-rating Depressive Scale (SDS)and Self-rating Anxious Seale(SAS).The multivariate analysis was used to assess the determinant factors.Results The study included 141 epilepsy patients in the teat group and 59 sex,age,and education matched normal controls. WHOQOL-BREF scores in the physical and psychological aspects were significantly lower in epilepsy patients(12.7 ±1.8 and 12.4±1.9,respectively)than those in the normal controls(15.1 ±2.3 and 13.9 ±1.9,respectively,t value were 11.75 and 8.625.both P<0.05).The survey reported that 57.4 % of the epilepsy patients suffered with depression.and 39.7 % anxiety.The patients with both anxiety and depression scored lower in all aspects in QOLIE survey except medical effect.Multivariate analysis showed that factors that effect the overall quality of life in order were anxiety.depression and disease duration.Conclusion Our results support that complications of anxiety and depression and long disease duration are key factors affecting the quality of life in epilepsy patients.