CAJ | 학술논문

通过酸碱处理活化NiTi合金表面,在模拟体液中仿生生长类骨磷灰石层以改善其生物相容性.采用电化学阻抗谱研究了预钙化对加速磷灰石沉积的影响,并基于双层模型建立了电子等效电路.结果表明:随着在模拟体液中浸泡时间的延长,化学处理的NiTi合金表面类骨磷灰石不断生长,并且添加预钙化试样浸泡3 d,即可在合金表面生长出均匀完整的类骨磷灰石层,而未预钙化试样表面沉积物稀少.对应电子等效电路中,预钙化试样电阻值明显大于未预钙化试样的,显示预钙化促进了活化NiTi合金表面类骨磷灰石的生长.
통과산감처리활화NiTi합금표면,재모의체액중방생생장류골린회석층이개선기생물상용성.채용전화학조항보연구료예개화대가속린회석침적적영향,병기우쌍층모형건립료전자등효전로.결과표명:수착재모의체액중침포시간적연장,화학처리적NiTi합금표면류골린회석불단생장,병차첨가예개화시양침포3 d,즉가재합금표면생장출균균완정적류골린회석층,이미예개화시양표면침적물희소.대응전자등효전로중,예개화시양전조치명현대우미예개화시양적,현시예개화촉진료활화NiTi합금표면류골린회석적생장.
In order to improve its biocompatibility, a biomimetic process that treats the NiTi alloy with acid and alkali separately, and then in a simulated body fluid (SBF) was employed to deposit a bone-like apatite coating on a NiTi surface. Effect of pre-calciflcation on accelerated apatite growth on the bioactive NiTi in the SBF was investigated using an electrochemical impedance spectroscopy (EIS). The electrical equivalent circuit based on a two-layer model was proposed. The results show that bone-like apatite is con-tinuously formed on chemically treated NiTi with increasing of immersion time in the SBF. After immersion in the SBF for 3 d, the surface of chemically treated NiTi with pre-calcification is covered with a high density of compact and uniform granules of bone-like apatite, while imperfect coating is observed on the sample surface without pre-calcification. The resistance of the apatite layer on the sample with pre-calcification is obviously higher than the one of the sample without pre-calcification, which indicates the bone-like apatite on chemically treated NiTi is promoted by the pre-calcification process.