CAJ | 학술논문

背景:调查研究发现,无论高血压人群还是正常血压人群,脉压差增大都是动脉硬化和心血管疾病危险度增大的标志之一.目的:通过对四川省1989名成年健康人群脉压差及其相关因素分析,探讨预防脉压差过大、降低心血管疾病发病率以及提高人群生活质量等问题.方法:采取分层、整群抽样,对1989名健康成年人进行问卷调查,并进行体质检查和血液生物化学血糖、肾功能以及血脂4项等检测,分析脉压差与各观察指标间的关系.结果与结论:男性、女性脉压差随年龄增加而增加,其中50岁以上人群,脉压差随年龄呈线性增加,空腹血糖、尿酸、血尿素氮、总胆固醇、三酰甘油、收缩压、舒张压随脉压差增大而增大,且年龄、BMI、腰臀比、三酰甘油与脉压差呈线性依存关系,脉压差与体育锻炼呈显著负相关.脉压差随着年龄、BMI、腰臀比、三酰甘油增加而增加,随着脉压差的增大,肾功能和血糖调节能力相对下降.提示,中老年人群需要通过合理饮食、运动控制向心性肥胖,从而控制脉压差,减小脉压差增大对肾脏功能损害,降低心血管疾病发病率.
배경:조사연구발현,무론고혈압인군환시정상혈압인군,맥압차증대도시동맥경화화심혈관질병위험도증대적표지지일.목적:통과대사천성1989명성년건강인군맥압차급기상관인소분석,탐토예방맥압차과대、강저심혈관질병발병솔이급제고인군생활질량등문제.방법:채취분층、정군추양,대1989명건강성년인진행문권조사,병진행체질검사화혈액생물화학혈당、신공능이급혈지4항등검측,분석맥압차여각관찰지표간적관계.결과여결론:남성、녀성맥압차수년령증가이증가,기중50세이상인군,맥압차수년령정선성증가,공복혈당、뇨산、혈뇨소담、총담고순、삼선감유、수축압、서장압수맥압차증대이증대,차년령、BMI、요둔비、삼선감유여맥압차정선성의존관계,맥압차여체육단련정현저부상관.맥압차수착년령、BMI、요둔비、삼선감유증가이증가,수착맥압차적증대,신공능화혈당조절능력상대하강.제시,중노년인군수요통과합리음식、운동공제향심성비반,종이공제맥압차,감소맥압차증대대신장공능손해,강저심혈관질병발병솔.
BACKGROUND:High pulse pressure is the signal of arteriosclerosis or cardiovascular diseases for both hypertension and normal blood pressure population.OBJECTIVE:The pulse pressure and related factors of healthy adults in Sichuan province were analyzed to explore the method for preventing excessive pulse pressure and improving the quailty of life.METHODS:Hierarchical,cluster sampling were performed in 1989 healthy adults.The physical examination,blood glucose,renal function and blood fat were detected,and the relation of pulse pressure and its related factors were analyzed.RESULTS AND CONCLUSION:Pulse pressure increased following the age.especially showed a linear increasing in those who more than 50-year-old The increased pulse pressure leaded to larger fasting plasma glucose,uric acid,blood urea nitrogen,total cholesterol,triacylglycerol,systolic pressure and diastolic pressure,in addition,the age,body mass index,waist-to-hip ratio,triacylglycerol and pulse pressure showed a linear relationship.But physical exercise was negative correlated to pulse pressure.With pulse pressure increasing,the renal function and regulating capacity of blood glucose was decreased The results suggested that mid-aged population should take reasonable diet and more physical exercise to prevent central obesity and excessive pulse pressure,reduce the risk of renal dysfunction and the incidence of cardiovascular disease.