世界中西医结合杂志
世界中西醫結閤雜誌
세계중서의결합잡지
WORLD JOURNAL OF TRADITIONAL CHINESE AND WESTERN MEDICINE
2009年
7期
499-501
,共3页
缺血性脑中风%抑郁症%加味四逆散%盐酸氟西汀
缺血性腦中風%抑鬱癥%加味四逆散%鹽痠氟西汀
결혈성뇌중풍%억욱증%가미사역산%염산불서정
Ischemic stroke%Depression%Jia Wei Si Ni San%Fluoxetine hydrochloride
目的 观察中西医结合方法治疗缺血性脑中风后抑郁症的临床疗效.方法 将95例患者随机分为对照组和治疗组.对照组44例给予内科常规治疗,同时予以盐酸氟西汀,治疗组51例在对照组治疗基础上给予加味四逆散水煎剂口服.观察两组患者的临床疗效、汉密尔顿抑顿量表(HAMD)评分、神经功能缺损程度评分变化及不良反应情况.结果 治疗组总有效率为90.2%,对照组为77.3%,治疗组疗效明显优于对照组(P＜0.01).治疗组与对照组治疗后HAMD 量表评分、神经功能缺损程度评分均较治疗前显著降低(P＜0.01),且治疗组的下降优于对照组(P＜0.05,P＜0.01).结论 中西医结合方法治疗缺血性脑中风后抑郁症疗效显著,且不良反应少,具有整体调节的优势.
目的 觀察中西醫結閤方法治療缺血性腦中風後抑鬱癥的臨床療效.方法 將95例患者隨機分為對照組和治療組.對照組44例給予內科常規治療,同時予以鹽痠氟西汀,治療組51例在對照組治療基礎上給予加味四逆散水煎劑口服.觀察兩組患者的臨床療效、漢密爾頓抑頓量錶(HAMD)評分、神經功能缺損程度評分變化及不良反應情況.結果 治療組總有效率為90.2%,對照組為77.3%,治療組療效明顯優于對照組(P＜0.01).治療組與對照組治療後HAMD 量錶評分、神經功能缺損程度評分均較治療前顯著降低(P＜0.01),且治療組的下降優于對照組(P＜0.05,P＜0.01).結論 中西醫結閤方法治療缺血性腦中風後抑鬱癥療效顯著,且不良反應少,具有整體調節的優勢.
목적 관찰중서의결합방법치료결혈성뇌중풍후억욱증적림상료효.방법 장95례환자수궤분위대조조화치료조.대조조44례급여내과상규치료,동시여이염산불서정,치료조51례재대조조치료기출상급여가미사역산수전제구복.관찰량조환자적림상료효、한밀이돈억돈량표(HAMD)평분、신경공능결손정도평분변화급불량반응정황.결과 치료조총유효솔위90.2%,대조조위77.3%,치료조료효명현우우대조조(P＜0.01).치료조여대조조치료후HAMD 량표평분、신경공능결손정도평분균교치료전현저강저(P＜0.01),차치료조적하강우우대조조(P＜0.05,P＜0.01).결론 중서의결합방법치료결혈성뇌중풍후억욱증료효현저,차불량반응소,구유정체조절적우세.
Objective To observe the clinical efficacy on depression after ischemic stroke treated with integrative Chinese and western medicine.Methods 95 cases were randomly divided into control group and treatment group.In control group(44 cases),conventional therapy of internal medicine was applied.Additionally,fluoxetine hydrochloride was administered.In treatment group(51 cases),on the basis of the treatment as control group,Ji Wei Si Ni San decoction was administered orally.The clinical efficacy,Hamilton Depression Scale(HAMD)score,the changes of neurological deficit score as well as the situation of adverse reactions were observed in two groups.Results The total effective rate was 90.2% in treatment group and 77.3% in control group.The efficacy of treatment group was superior apparently to that of control group(P＜0.01).After treatment,HAMD score,neurological deficit score in either treatment group or control group reduced significantly compared with those before treatment(P＜0.01).The score decrease in treatment group was superior to that of control group(P＜0.05,P＜0.01).Conclusion Integrative Chinese and western medicine is significant in the efficacy on depression after ischemic stroke,less in adverse reactions and advantageous in holistic adjustment.
