CAJ | 학술논문

目的:比较研究宫颈癌术后调强放疗(IMRT)和常规四野(4F)或二野(2F)放疗时靶区及其周围危及器官受照剂量的差异.方法:随机选择6例宫颈癌术后患者,进行CT扫描、靶区和危及器官的勾画,用三维治疗计划系统进行常规4F、常规2F和MRT计划设计,并对结果进行比较分析.结果:PTV适形度,IMRT计划优于常规4F计划,P=0.015,常规4F计划优于常规2F计划,P=0.043,差异具有统计学意义(p＜0.05).与常规计划4F或2F相比,IMRT计划的膀胱50%体积受照剂量平均下降了25.8%和27.5%,直肠50%体积受照剂量平均下降了12%和14.3%,小肠50%体积受照剂量平均下降了36.5%和50%,而左、右股骨头和髂骨的差异无统计学意义.结论:在宫颈癌术后放疗中,IMRT技术较常规放疗技术有剂量学方面的优越性.
목적:비교연구궁경암술후조강방료(IMRT)화상규사야(4F)혹이야(2F)방료시파구급기주위위급기관수조제량적차이.방법:수궤선택6례궁경암술후환자,진행CT소묘、파구화위급기관적구화,용삼유치료계화계통진행상규4F、상규2F화MRT계화설계,병대결과진행비교분석.결과:PTV괄형도,IMRT계화우우상규4F계화,P=0.015,상규4F계화우우상규2F계화,P=0.043,차이구유통계학의의(p＜0.05).여상규계화4F혹2F상비,IMRT계화적방광50%체적수조제량평균하강료25.8%화27.5%,직장50%체적수조제량평균하강료12%화14.3%,소장50%체적수조제량평균하강료36.5%화50%,이좌、우고골두화가골적차이무통계학의의.결론:재궁경암술후방료중,IMRT기술교상규방료기술유제량학방면적우월성.
Objective:To compare the dosimetric differences of the planning target volume(PTV)and the organs at risk(OAR)for postoperative patients with cervical cancer on intensity-modulated radiotherapy(IMRT)and conventional 4 fields(4F)or 2 fields(2F)radiotherapy.Methods:Six postoperative patients with cervical cancer were chosen randomly.The next steps were CT scan,PTV and OAR contouring.The treatment protocols were designed into conventional 4F,2F and IMRT by TPS.Finally,the doso distribution and DVH were compared.Results:About the conformability of PTV,IMRT showed a significantly superior dose distribution over conventional 4F(P=0.015),and conventional 4F was superior to 2F(P=0.043).IMRT as compared with conventional 4F or 2F protocols,the received dose of the 50%volume of bladder was reduced by 25.8%and 27.5%,the rectum was reduced by 12%and 14.3%,the small intestine was reduced by 36.5%and 50%.But the differences of the femoral head(left & right)and the ilium have no statistical significance.Conclusion:in postoperative radiotherapy for cervical cancer,IMRT have Inore dosimetric advantages than conventional radiotherapy.